Scientist - in vivo

We are seeking a highly-motivated and independent Scientist with a BS and at least 3 years of research experience in Cellular Therapy, Immunology, and/ or Immuno-Oncology to join our rapidly growing Cell Therapy Team. In this role, you will contribute to advancing innovative Cell Therapy products by designing and conducting laboratory experiments, developing methodology, and generating and interpreting scientific data in a highly collaborative environment.Expertise in in vivo studies and T cell biology is critical for this role.A successful candidate must be well-organized and must keep an excellent written record of their work.

Basic Accountabilities:

• Conducts hands-on in vivo research

• Contributes to the plans and designs of in vivo studies

• Conducts routine in vitro experiments 

• Communicates the results to team members and is involved in the interpretation of data

• Supports a team and works collaboratively with project managers to ensure the efficient relay of information and forward translation of data

• Provides technical instruction to the team and allocates administrative work where possible

Education, Qualifications, Skills, and Experience

Required Education

• BS in a relevant scientific field with 3+ years of research experience or MS and 2 years in Immunology, Cancer Biology, Cell Biology, or related field

Essential requirements

• In vivo skillset including animal handling, mouse tumor models, standard routes of dosing and engraftment

• Proficiency in cell culture of established cell lines and primary human immune cells

• Hands-on expertise in T-cell functional characterization assays, including in vitro cytotoxicity, proliferation, and cytokine measurement

• Experience in the execution and analyses of flow cytometry experiments

Preferred qualifications

• Ability to lead a small in vivo science project

• Problem-solving skills related to in vivo research and data analysis

• Transfection/transduction and expansion of primary cells

• Basic experience in developing cellular therapies, including CAR-T/CAR-NK, TCR-T therapies, and/or TIL therapies.

• CRISPR/genome editing experience

• Biotechnology or pharmaceutical industry experience preferred

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you’ll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.

Competitive remuneration and benefits apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.

Where can I find out more-

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

The annual base pay (or hourly rate of compensation) for this position ranges from $ 87,200.00 - 130,800.00 USD Annual. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. ​