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Senior Scientist Model Development

Location Waltham, Massachusetts, United States Job ID R-227924 Date posted 28/05/2025

Job Title:Senior Scientist Model Development

Location: Waltham, MA

At AstraZeneca, we're embarking on an exciting new frontier in medical science – the quest to extend human healthspan. Our newly formed Aging Research Group is at the forefront of this groundbreaking initiative, aiming to develop innovative therapeutics that not only add years to life but life to years. We are seeking a highly motivated Senior Scientist to join our newly formed, dynamic team.

As a key member of our compact yet growing group, you'll play a pivotal role in developing models for elucidating mechanism of action and drug discovery. At AstraZeneca, you'll have the opportunity to make a significant impact on the future of healthcare while working in a collaborative environment at the cutting edge of research. The ideal candidate will thrive in this setting, contributing to our growth trajectory as we build our evolving team.

Key Responsibilities

  • Work closely with CROs to design and develop in vivo models for elucidation of aging biology

  • Design, develop, and optimize cell-based assays to validate mouse models

  • Assist in management of CRO activities for in vivo efficacy studies

  • Stay current with the latest developments in aging biology and translate new findings into actionable research strategies

  • Present findings to both internal teams and external collaborators/conferences

  • Contribute to patent applications and scientific publications

Qualifications

  • PhD in a relevant field with 1-4 years post-graduate experience or MS in a relevant field with 3-5 years post-graduate experience or BS in a relevant field with more than 5 years post-graduate experience

  • Demonstrable experience working with CROs to develop assays and/or mouse models with delivery of high-quality data

  • Extensive experience in designing, executing, and interpreting in vivo and cell-based assays

  • Outstanding communication and interpersonal skills with the ability to build effective relationships in a small team setting

  • Excellent analytical and problem-solving skills

  • Proven track record of scientific publications and/or patents in relevant fields

Desired Skills and Attributes

  • Strong background in aging biology and deep familiarity with key pathways and mechanisms involved in the aging process

  • Self-driven with the ability to work independently and as part of a team

  • Adaptable and comfortable with changing priorities in a fast-paced research environment

  • Familiarity with in vivo models of longevity and healthspan

Why Join AstraZeneca?

At AstraZeneca, we believe in pushing the boundaries of science to deliver life-changing medicines. Our work in aging and healthspan is a testament to our commitment to innovation, collaboration, and making a real difference in patients' lives.

We offer you the opportunity to:

  • Contribute to high-impact science at the intersection of aging and therapeutics.

  • Work with a team of world-class scientists in a supportive and inclusive environment.

  • Grow your career through continuous learning and diverse project exposure.

Benefits

We provide a competitive Total Rewards package that includes:

  • Base salary, annual bonus, and long-term incentive opportunities

  • Comprehensive health and wellness benefits

  • Generous paid time off and flexible working options

Learn More

Diversity and Inclusion

AstraZeneca is proud to be an equal opportunity employer. We value and embrace diversity and are committed to building an inclusive team that reflects a broad range of backgrounds, perspectives, and experiences.

If you require a reasonable accommodation for the application or interview process, or for performing essential job functions, please let us know.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

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Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.