Senior Scientist, Bioscience Assays & Automation

Are you an experimental scientist with a passion for accelerating research and development through high-quality assays and automation? Join our Assay & Automation Team within the Bioscience Technology Division and contribute to scientific discovery in Cardiovascular, Renal, and Metabolism (CVRM) by delivering robust RNA, and metabolite analyses. 

The Early CVRM department discovers and develops new medicines in cardiovascular, renal, and metabolic diseases. Our Bioscience Technology Division is a hub for technologies and innovation, partnering across disease areas to enable target discovery and translational research. We specialize in Bioscience Assays & Automation, Histology & Imaging, Next-Generation Platforms, and Data Analysis & Bioinformatics. 

Accountabilities:

As a Senior Scientist in the Assay & Automation Team, you will be responsible for generating high-quality molecular and biochemical data to support target identification, model validation, and mechanistic studies. Your leadership in method development and operational excellence will be instrumental in advancing CVRM projects and the broader Bioscience strategy. 

You will work at our vibrant R&D site in Gothenburg, Sweden, collaborating closely with multidisciplinary project teams. 

In collaboration with project scientists and data analysts, the role involves: 

• Sample processing: extraction ofRNA andmetabolitesfrom tissues, cells, and blood, following standardized procedures and Good Laboratory Practice. 

• RNA analysis: performingQuantitative PCR (qPCR)for gene expression profiling, assay optimization, validation, and quality control. 

• Metabolite/clinical chemistry: runningclinical chemistry assays on the Pentra platform, ensuring accurate and reproducible results aligned with study requirements. 

• Assay development and automation: designing, optimizing, and troubleshooting assays; contributing to automation workflows and throughput improvements. 

• Data integrity and reporting: ensuring data quality, documentation, and timely delivery of results; communicating findings to project teams and non-expert stakeholders. 

• Continuous improvement: establishing best practices, evaluating new methods and consumables, and contributing to technology onboarding and harmonization across labs. 

Essential Skills/Experience:

• MSc or PhD in molecular biology, biochemistry, biotechnology, or a related field, with substantial hands-on industry or academic experience in assay execution and lab automation.

• Demonstrated experience (minimum one year) in RNA and metabolite extraction from various tissues, cells, and blood.

• Applied experience in qPCR (design, optimization, validation, and data analysis).

• Practical experience with Pentra clinical chemistry analyzers or equivalent platforms for metabolite/biochemical assays.

• Track record of developing, optimizing, and troubleshooting assays; familiarity with SOPs, QC metrics, and method transfer.

• Experience implementing improvements in throughput, reproducibility, and sample logistics; familiarity with lab instrumentation and automation principles.

• Ability to communicate clearly with cross-functional teams, document methods and results, and present data to non-experts.

• Proactive, organized, and able to work with minimal supervision in a fast-paced environment; strong teamwork and interpersonal skills.

Desirable Skills/Experience:

• Hands-on experience with capillary western blotting system (quantitative protein analysis), immunoassay, multiplex, or high-throughput platforms; experience with liquid handling automation.

• Network of academic/industrial collaborators; experience with method transfer across sites or CROs.

At AstraZeneca, we are driven by curiosity and courage to explore the unknowns of science. Our commitment to making a difference is fueled by our passion for scientific innovation. We integrate data and technology to achieve breakthroughs that redefine healthcare. Our inclusive environment encourages collaboration across academia, biotechs, and industry to create swift impacts on disease. With opportunities for continuous learning and growth, we empower our team to think differently and make bold decisions that impact patients' lives globally.

Ready to make an impact? Apply now to join our team of innovators!Welcome with your application no later than October 26th, 2025.We will review the applications and conduct interviews continuously, so please apply as soon as possible.