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Executive Director, Global Clinical Head – Rheumatology Cell Therapy

Location Gaithersburg, Maryland, United States Job ID R-233386 Date posted 17/09/2025

Join AstraZeneca, a global, science-led biopharmaceutical company, and make a more meaningful impact on patients' lives around the globe. We are seeking a Senior Medical Director in Immunology Cell Therapy to craft and deliver our Immunology Cell Therapy pipeline and lead innovative clinical stage cell therapy programs. This is an excellent opportunity for a motivated drug developer to pioneer the next wave of science, focusing on outcomes and shaping the patient ecosystem.

The Global Clinical Head – Rheumatology Cell Therapy (GCH-RCT) is accountable of all the clinical development aspects related to one or more programs of cell and gene therapy in rheumatology indications across multiple geographies, spanning from Ph1 to Ph2/3 with registrational intent. Additionally, the GCH-RCT is expected to influence the overaching strategy of AstraZeneca in the rheumatology space, with emphasis on new platforms for cell and gene therapy. The job includes direct people management responsibilities of a group of physicians and/or clinical scientists involved in study-related activities. The GCH-RCT reports directly into the VP of Immunology Cell Therapy (ICT) and sits in their Leadership Team.

Accountabilities:

  • Represents the clinical development function at Global Project Team (GPT) level

  • Accountable for the clinical development strategy and execution within the Clinical Project Team (CPT)

  • Represents Rheumatology in the ICT-LT, and in other strategic committees

  • Coordinates the activities of physicians/clinical scientists involved in the different clinical studies and mentors them in their career development

  • Provides input to the development strategy from a medical and clinical perspective

  • Leads or oversees a diverse range of initiatives to improve quality, integrity of information interpretation, cost or time and where appropriate lead the development of new methodology or process to provide business benefit

Education, Qualifications, Skills and Experience

  • Medical degree

  • Professional qualification in Rheumatology

  • Relevant experience in the field of rheumatology and

  • 15+ yrs experience in the pharmaceutical or biotech sector (in the absence, significantly longer experience in the academic/non-profit setting)

  • Significant understanding of the overall drug development and commercialization process

  • Demonstrated ability to set and manage priorities, resources, performance targets and project initiatives in a global environment

  • Conceptual, analytical and strategic thinking

  • Ability to influence strategically and persuade tactfully, to obtain desired outcomes while maintaining effective, positive, organizational relationships

Desirable Skills

  • PhD in immunology, rheumatology or cell & gene therapy, or equivalent academic/non-profit experience/post

  • Extensive knowledge of the latest technical and regulatory developments

  • Operational expertise in risk management and contingency planning

  • Familiarity with the latest research and thinking

  • Effective problem and conflict resolution skills and proven team focus

  • Excellent knowledge of AstraZeneca policies, procedures and guidelines

At AstraZeneca, we trust in the science. Driven by it and united by it, this is the place where extraordinary science comes alive. It's our smart thinking and patience that helps us to push the boundaries of science to deliver life-changing medicines. If you have a true love of science and believe in its potential to redefine the possible, then this is the place for you.

Join us at AstraZeneca's Biopharmaceuticals R&D division and be part of a team of leading specialists driven to pursue scientific knowledge. Here, we see the bigger picture and know where we can make the biggest impact. We're strong storytellers and communicators, showcasing our work across the business to gain agreement and bring others on the journey with us.

Are you ready to make a greater impact? Apply now!

Date Posted

18-Sep-2025

Closing Date

16-Nov-2025

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.