All Stream Process Lead

All Stream Process Lead

Are you passionate about science and eager to make a difference in the world of medicine? At AstraZeneca, we are committed to transforming ideas into life-changing medicines by following the science. As an All Stream Process Lead, you will play a pivotal role in our Clinical production team within Biopharmaceutical Development. Here, you'll gain comprehensive knowledge of bioprocessing in a cGMP and process development environment, contributing to the acceleration of product candidates into the clinic. Join us in a collaborative and dynamic team where your adaptable, science-driven approach will be valued and your expertise in cell culture, purification, and critical support activities will be honed.

Accountabilities:

• Serve as the Process Execution Subject Matter Expert for your processing area, representing all shifts and/or functional areas as needed for investigations, CAPAs, and tech transfer information.
• Provide in-direct floor support (50-70% time) including investigation representation, CAPA execution, process performance trending, batch record review and approval, training assessment and provision, liaison between process scale-up and cGMP, troubleshooting support, and process improvement execution.
• Offer direct on-floor support (30-50% time) with proficiency in relevant process operations and lead manufacturing execution.

Essential Skills/Experience:

• Bachelor's degree in a science or engineering field with minimum 4+ years' biotechnology or pharmaceutical industry experience
• Work is performed without appreciable direction
• Applies technical knowledge and expertise to achieve project targets in a timely fashion and to agreed quality standards
• Develops and maintains a level of scientific knowledge and capability, perhaps extending to specialist expertise in a specific area of work
• Logic and decision-making abilities, critical thinking and troubleshooting skills; effects of decisions are long-lasting and influence the future course of the organization
• Contacts are frequent with individuals representing other departments, excellent verbal and written communication skills
• Contacts involve obtaining or providing information or data on matters of moderate importance to the function of the department or which may be of sensitive nature, requiring some explanation or interpretation
• Ability to work with others in a team environment and lead a team of peers
• Proficient in cell culture operations such as Biosafety Cabinet Operation, Cell Banking, Bioreactor Operations, Aseptic Technique, and POD Harvest Operations.
• Proficient in solution preparation operations such as media preparations and buffer preparations.
• Proficient in downstream operations such as column packing, column chromatography, viral inactivation, TFF, and Bulk Fill operations.

Desirable Skills/Experience:

• Dynamic individual with the ability to communicate and engage others.
• Independent and self-starting. Ability to work with minimal supervision.
• Experience in biologics process development and/or cGMP manufacturing
• Demonstrate a high level of drive and initiative.
• Helps to develop new and innovative techniques and methodologies for ways of working within area
• Experience in investigation and troubleshooting methodology
• Demonstrate leadership, organization and time management skills.
• Demonstrate flexibility and willingness to change ways of working
• Continuous manufacturing processing experience

At AstraZeneca, we embrace the variety of challenges that come with working across all stages of development on diverse molecules. This dynamic environment not only keeps our work interesting but also empowers us to expand our skills and knowledge. Our commitment to innovation drives us to think broadly about patients' needs, enabling us to develop progressive solutions that prevent and treat diseases effectively. We value our influential role in shaping drug development strategies and gaining fast approvals, ensuring our groundbreaking science reaches patients swiftly.

Ready to make an impact? Apply now to join our team at AstraZeneca!

The annual base pay for this position ranges from $103,286.40 - 154,929.60. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. 

Date Posted

26-Jun-2025

Closing Date

30-Jul-2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. ]]>