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Senior Scientist, Process Modelling

Location Durham, North Carolina, United States Job ID R-234266 Date posted 27/08/2025

Senior Scientist, Process Modelling  

At AstraZeneca, we win through the science, it is at the heart of our every success. Every decision is rooted in the limitless possibilities of what science can do. We push the boundaries of science to deliver life-changing medicines. This purpose underpins everything we do. It gives us a reason to come to work every day. It reminds us why we exist as a company. It helps us deliver benefits to patients and build new value for shareholders. It also sets the context for our employees’ activities and the roles of our teams, partners, and other collaborators. AstraZeneca has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.

Introduction to role:

Are you ready to make a difference in the world of drug development? As a Senior Scientist in Process Modelling at AstraZeneca, you'll collaborate with digital specialists, scientific authorities, and project leaders across our global network. Your mission? To champion sophisticated modelling solutions and propel drug development from clinical trials to commercial production. Dive into the challenge and be part of a team that transforms ideas into life-changing medicines!

Accountabilities:

  • Translate sophisticated pharmaceutical process problems into robust mechanistic models, providing actionable insights to accelerate drug development projects.
  • Collaborate with experimental scientists from a diverse group of backgrounds to uncover new modelling opportunities and strategically guide experimental design.
  • Establish strong, collaborative relationships within the digital and broader product development communities to improve the progressive impact of modelling and simulation.
  • Drive organizational digital transformation by advancing standard processes and advocating for the application of ground breaking digital tools, including making them available to agentic AI systems.
  • Develop, validate, and deploy modelling and simulation protocols to support scientists across the wider scientific community.

Essential Skills/Experience:

  • Master’s with 4+ plus years or a PhD in chemical engineering, mechanical engineering, or related discipline, ideally with specialization in process modelling.
  • Extensive knowledge of process modelling fundamentals and demonstrable experience applying these principles to the development of industrial-scale products or processes.
  • Proficiency in programming and simulation tools (such as Python, Matlab, gPROMS), with a readiness to explore new technologies.
  • Strong collaboration, communication, influencing, and networking skills.

Desirable Skills/Experience:

  • Proven experience within pharmaceuticals, biopharmaceuticals, food, cosmetics, personal care, or consumer goods.
  • Experience with one or more of the following techniques: process modelling, discrete element modelling, computational fluid dynamics, system modelling, multiscale modelling, molecular dynamics.
  • Comprehensive understanding of process equipment and technology.
  • Demonstrated ability to proactively introduce and apply novel modelling approaches to advance product development and manufacturing.
  • A track record of scientific publications in the field of modelling and simulation.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base pay for this position ranges from $110,687 to $166,031. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

At AstraZeneca, we are driven by a passion for innovation and a commitment to transforming lives. Our unique approach combines the agility of a biotech with the resources of a global biopharma. We are dedicated to pushing boundaries in rare disease biopharma, translating complex biology into transformative medicines. Our culture is rooted in integrity and inclusiveness, fostering an environment where ideas flourish and new thinking grows. Here, your career is not just a path but a journey to making a difference where it truly counts.

Ready to join a team that makes an impact? Apply now and be part of our journey!

Date Posted

28-Aug-2025

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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Glassdoor logo Rated four stars on Glassdoor

Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.