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Quantitative Systems Pharmacology Internship

Location Cambridge, England, United Kingdom Job ID R-244511 Date posted 27/01/2026

Quantitative Systems Pharmacology Intern

Cambridge

About AstraZeneca

AstraZeneca is a global,science-ledbiopharmaceutical business and its innovative medicines are used by millions of patients worldwide! AstraZeneca Summer Internships introduce you to the world of ground-breaking drug development, embedding you in highly dedicatedteams,committed to delivering life-changing medicines to patients. Our 10–12-week program is designed for undergraduate, master's, and doctoral students. We offer exciting opportunities across Research & Development, Operations, and Enabling Units (Corporate functions).

Our internships immerse students in the pharmaceutical industry, allowing the opportunity to contribute to our diverse pipeline of medicines whether in the lab or outside of it. You will feel trusted and empoweredtotakeonnewchallenges, but with all the help and guidanceyouneedtosucceed. This internship will help you developessential skills, expand your knowledge, and build a network that will set you up for future success. You will be surrounded by curious,passionate, and open-minded professionals eager to learn and follow the science, fostering your growth in a truly collaborative and globalteam.

Job Title:
Quantitative Systems Pharmacology - Mathematical modellingofdrug biodistribution insolidtumors

The objective of the project will be to assist in the development and testing of our platform for MRI-informed modelling prediction of drug penetration in solid tumors, which will be developed as a collaboration between the Systems Medicine and Integrated Bioanalysis teams.

Data extracted from non-invasive MRI imaging will be used to parametrize transport properties of therapeutic antibodies for anti-cancer therapy, and build spatial mathematical models of solid tumors, to optimize dosing decision in anti-cancer therapies.

We are seeking a candidate with a keen interest in numerical simulations of mathematical models applied to biology.

Accountabilities:
  • Review the relevant literature
  • Extract, and processing and visualizing data from MRI imaging and/or spatial transcriptomics.
  • Assistinthedevelopment/implementation of spatialmathematicalmodels drug biodistribution in tumor
  • Report results and prepare presentations to communicatewithrelevantscientific teams within AZ

Essential:
  • Solidunderstanding, at advancedundergraduate level or above, of multivariate calculus and linear algebra;
  • Basic coding proficiencyin at least one of the following: Python (preferred), Julia, Matlab, R, C/C++

Desirable:
  • Somepreviousexposuretonumerical methods for partialdifferentialequations (PDEs), for example diffusion, diffusion-reaction and advection-diffusion-reaction problems.
  • Somepreviousexposureto analysis of 3D spatial data.

Given the comparatively challenging nature of the subject matter we are looking for either a brightadvanced undergraduate or master student.

AstraZeneca is where you can immerse yourself in groundbreaking work with realpatient impact.

Trusted to work on important projects, you’ll have the independence totakeonnewchallenges while receiving all the guidanceyouneedtosucceed. Our collaborativeenvironment is designed to help you growprofessionally and personally, surrounded by passionate individuals eager to makeadifference.

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca, starting with the recruitment process. Wewelcome and consider applications from all qualified candidates, regardless of characteristics.
We offer reasonableadjustments/accommodations to help all candidates to perform at their best. If you have a need for any reasonableadjustments/accommodations, please complete the section in the application form.

Ready to make an impact? Apply now and join us on this excitingjourney!

#Earlytalent

Date Posted

26-Jan-2026

Closing Date

09-Feb-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

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