Diagnostic Senior Scientist

Job Title: DiagnosticSenior Scientist

Location: Cambridge, UK

Salary: Competitive + excellent benefits!

Introduction to the Role:

Are you an experienceddiagnostic scientistwith a passion to apply your skills and bring technicalexpertiseand scientific innovation to develop diagnostics for use in a clinical setting? If so, this could be the role for you!  

AstraZeneca delivers companion and complementary diagnostic assays that match medicines to those patients who are most likely tobenefitfrom them. This approach, known asPrecision Medicine, is based on those individual characteristics that make some patients respond to treatment better than others. We use this knowledge to develop diagnostic tests that doctors can use to help prescribe the best treatment for each patient. 

About the Role:

As aSenior Scientist, Diagnostics Science, you will use your knowledgeofoncology diagnostic technologiesand approachesincluding fore.g. Immunohistochemistry (IHC),multiplex IHC and proteomics,digital pathology,Next Generation Sequencing (NGS)etc. to providescientific and technical expertiseto deliver innovative diagnostic approaches to AstraZeneca’s clinical portfolio, through strategic partnerships with leading diagnostic companiesand laboratory-based science delivery.

The role holder will be accountable for:

• Deliveryof diagnostic science and innovation projects, through close collaboration with the cross-functional teams.

• Building andmaintaininga knowledge of current andnew technologiesin diagnostics, with a particular focus on oncology, and seeing opportunities for innovation and internal/external collaborations.

• Developing innovative diagnostic science proposals across core therapeutic areas .

• Evaluating the performance of novel diagnosticsthrough delivery of diagnostic feasibilitystudiesand laboratory-based scienceto timelines and budget.

• Providing scientific and strategic feedbackintoprecision medicine approaches for diagnostic and drug product teams.

• Ensuring that all activities are delivereddemonstratingbehaviours and values aligned to AstraZeneca Code of Conduct and supporting policies,standardsand procedures, including compliant management of Budget, Safety,Healthand Environment .

Education, Qualifications,Skillsand Experience:

Essential:

• Masters / PhD or equivalent experience in a relevant subject.

• Record of delivery in a scientific capability, including peer-reviewed publications.

• Expertisewith one or moreof these technologies (for example, but not limited to: IHC,digital pathology, NGS, PCR).

• Excellent knowledge of current technology trends inoncologydiagnosticsand precision medicine.

• Experience of working with external partners or collaborators (ideally academic investigators and diagnostic companies).

• Ability to communicate with cross-functional stakeholders for project updates through oral presentations and progress reports.

Desirable:

• Good computational and data analysis skills enablingautomated/semi-automatedanalysis of large datasets (e.g. using AI,softwareand programming languages).

• Experience developing diagnostic assays in a regulated environment e.g. under In Vitro Diagnostics development standards or within a CAP/CLIA laboratory.

• Experience of leading projects within a diagnostic or drug development organisation.

• An understanding of drug and companion diagnostic assay co-development and commercialisation and experience working in early and/or late phase projects.

• Demonstrable experience of analytical diagnostic assay validation,use in a clinical testing setting and /ordelivery of regulatory submission.

• Knowledge of requirements related to handling of Human Biological Samples.

About AstraZeneca:

At AstraZeneca, we don’t just follow the science — we lead it. Every day, we push boundaries to deliver the next generation of cancer medicines faster and smarter.

We’re a global, science-driven company with a bold ambition: to transform cancer care and eliminate cancer as a cause of death. In Oncology, we take on some of the toughest challenges in medicine, using cutting-edge science, advanced technologies, and strategic partnerships to accelerate progress.

Here, you’ll be part of a team that’s fearless in pursuit of innovation — where your ideas matter, your work has real impact, and your curiosity is encouraged at every step.

Where can I find out more?

Our Social Media:

• Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

• Follow AstraZeneca on Facebookhttps://www.facebook.com/astrazenecacareers/

• Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en