Global Clinical Program Lead, Multiple Sclerosis, Immunology Cell Therapy

Location: Office based role in Boston Seaport MA, USA

Are you a visionary expert in clinical drug development, possessing the capabilities to drive a successful strategy in accelerating the development of cellular therapies for patients with immune-mediated diseases? Are you dedicated to revolutionizing the treatment of immune-mediated diseases and creating a significant impact on patients' lives? Do you have a strong passion for science and substantial clinical development experience in Immunology and CAR-T cell therapies? Do you possess both strategic and operational leadership skills? If so, we invite you to join us! We are currently seeking a Global Clinical Program Lead, Multiple Sclerosis, Immunology Cell Therapy to be based in Boston Seaport.

About AstraZeneca

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. We are more than one of the world’s leading pharmaceutical companies.

Immunology Cell Therapy

Our ambition is to build a world class organization that accelerates the delivery of transformative cell therapies for patients with immune mediated diseases. It’s our big vision that unites and inspires us. Cell therapies represent a fundamental evolution of how drugs are discovered, developed and manufactured, these new advanced potentially curative cellular modalities require a new development strategy to ensure their rapid availability to patients. With multiple autoimmune and inflammatory indications and clinical stage cell therapies in global development, we keep pushing forward.  Focusing on cutting-edge science with the latest technology to achieve breakthroughs.   AZ is a place built on courage, curiosity and collaboration – we make bold decisions driven by patient outcomes.

What You’ll Do

As a Senior Medical Director for Multiple Sclerosis, you will provide medical and scientific input to T-cell therapy clinical stage assets in multiple sclerosis and neurology. You will take responsibility for clinical development in cross-functional teams to support early to late-phase clinical development activities. These include the creation of overall clinical development plans and clinical study design, writing study concepts and protocols, key study and health authority documentation, medical monitoring and ensuring timely delivery of studies.

Essential Skills/Experience:

• An MD, or other equivalent degree from an accredited university or an MD or equivalent degree plus a PhD.

• 5 or more years of industry or combined academic/industry experience in clinical development.

• Significant experience in early and/or late phase clinical development.

• Closely follow medical developments within assigned areas, including cell therapy for autoimmune/inflammatory diseases, and disseminate new information within Clinical Development and wider organization, to transform trends and emerging data into agile clinical plans

• Work closely and collaborate across early and late clinical development, partner functions and wider AZ organization to ensure design and delivery of clinical development plans with high quality and speed

• Significant experience in the authoring of relevant regulatory documents.

• Detailed understanding of the full drug development process.

• Global external awareness within the therapeutic area and global regulatory environment

• Detailed understanding of clinical research methodology and biostatistics principles.

• Thorough command of FDA, EMA, MHRA and ICH GCP guidelines.

• Attention to detail, strive to generate high-quality work, and sense of passion and urgency to achieve team and program goals.

• Demonstrated experience leading complex projects.

• Demonstrated track record in delivering results.

• Outstanding verbal and written communication skills.

• Excellent analytical, problem solving and strategic planning skills.

Desirable Skills/Experience:

• Experience in clinical development of T-cell therapy is desired.

• Experience in immune-mediated diseases/clinical immunity is preferred.

At AstraZeneca, we trust in the science. Driven by it and united by it, this is the place where extraordinary science comes alive. It's our smart thinking and patience that helps us to push the boundaries of science to deliver life-changing medicines. If you have a true love of science and believe in its potential to redefine the possible, then this is the place for you.

Join us at AstraZeneca's Biopharmaceuticals R&D division and be part of a team of leading specialists driven to pursue scientific knowledge. Here, we see the bigger picture and know where we can make the biggest impact. We're strong storytellers and communicators, showcasing our work across the business to gain agreement and bring others on the journey with us.

Are you ready to make a greater impact? Apply now!

The annual base pay (or hourly rate of compensation) for this position ranges from $265,000 to $390,000. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.