Senior Manager, Epidemiology

The Epidemiology team at Alexion-AstraZeneca Rare Disease Unit is globally accountable for developing scientifically rigorous epidemiology forecasts of incidence, prevalence, and patient population size. These forecasts deepen our understanding of diseases, support strategic decision-making, and ultimately help Alexion transform the lives of people affected by rare diseases. As a Senior Manager, Epidemiology, you will play a crucial scientific role in collaborating with key business stakeholders globally to identify and prioritize opportunities for impactful epidemiologic forecasts across various therapeutic areas. You will be responsible for planning, developing, and executing epidemiological forecasts that characterize the incidence, prevalence, natural history, and estimated population size of pipeline and marketed indications. Additionally, you will communicate and interpret the results of these forecasts to ensure shared understanding and buy-in across the business. You will also lead or participate in functional excellence initiatives to improve our work and solve problems together.

Accountabilities:

• Collaborate with key business stakeholders to identify opportunities for epidemiological forecasting, negotiating timelines, and agreeing on fit-for-purpose deliverables.

• Accountable for systematic identification and critical appraisal of epidemiological literature and real-world data sources to characterize incidence, prevalence, natural history, and phenotype/genotype associations for assigned diseases.

• Perform epidemiological analyses to estimate and forecast prevalent and/or incident population sizes.

• Identify and oversee the analysis of external databases to estimate incidence and prevalence for disease areas.

• Summarize results in written reports and oral presentations.

• - Represent the Epidemiology department in cross-functional team meetings with presentation of summary findings to Alexion senior management and/or external stakeholders.

• Participate in the review and assessment of Epidemiology department processes including standardized templates for disseminating results of epidemiology population forecasting deliverables.

• Maintain awareness of epidemiology with respect to regulatory requirements, payer trends, and advancement of pharmacoepidemiology methods.

• Travel may be required (up to 10%).

Essential Skills/Experience:

• PhD / DSc / DrPH in Epidemiology or MPH/MSc in Epidemiology with at least 3 years experience in the pharmaceutical industry, biotechnology, or consulting environment.

• The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem-solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

Desirable Skills/Experience:

• Excellent oral and written communication skills.

• Knowledge of drug and clinical development process for genomic medicines.

• Excellent attention to detail and quality, and scientific rigor.

• Strong interpersonal skills and ability to work effectively in multidisciplinary teams.

• High degrees of self-motivation and organization.

• Comfort in a fast-moving environment with frequent changes in scope or direction of projects.

• Thorough and up-to-date technical knowledge of epidemiology and relevant biostatistics methods.

• Record of high-quality publications in peer-reviewed journals.

At Alexion, AstraZeneca Rare Disease Unit, you will join a company where 'Here it means more' is more than a statement; it’s an ethos. We are a beacon in the global Biopharmaceutical landscape. Our closeness to patients brings us closer to our work and each other. Combined with our brave, pioneering spirit – we are truly unique in R&D and healthcare. Grow and innovate in a business with a rapidly expanding portfolio. Enjoy the entrepreneurial spirit and autonomy of a leading biotech. You’ll join an energizing culture where people build connections to explore new ideas and learn. As an important member of our commercial team, you'll meet the needs of some of the most underserved patients in the world. You will be empowered with tailored development programs designed not just for skill enhancement but for fostering a deep understanding of our patient's journeys. Supported by exceptional leaders and peers ready to lift you in marketing, compliance, and beyond.

If this sounds like a team you want to be a part of, then we’d love to talk.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.