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HTA Modelling Science Director

Posted date Nov. 13, 2024
Contract type Full time
Job ID R-213068
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Why choose AstraZeneca Spain?

AstraZeneca Spain is a rising force in our global business. With headquarters in Madrid and our global hub in Barcelona, we’ve become an important international centre of excellence in the fight against critical disease. Boasting vibrant universities and business schools, the Barcelona ecosystem is a place where scientists can thrive. We attract a diverse workforce from across the globe, shining a beacon for innovation in a country that’s committed to clinical development.

We invite you to bring your talents to Barcelona where our respiratory medicine R&D and Global Marketing centre offers opportunities in R&D, IT, Commercial and HR. Or join us in Madrid and shape our growth in our BUs (Respiratory, Oncology & CVRM ), and a range of Corporate functions. Additionally, you can find sales roles throughout the country. Together, we’re contributing to a world-leading pipeline of therapeutics and delivering life-changing medicines to patients.

Who do we look for?

Calling all tech innovators, ownership takers, challenge seekers and proactive collaborators. At AstraZeneca Spain, breakthroughs born in the lab become transformative medicine for the world's most complex diseases. Alongside technical expertise, colleagues have the resilience, energy and collaborative mindset to change lanes, work with different teams and start projects from scratch.

Here, diverse minds and bold disruptors can meaningfully impact the future of healthcare using cutting-edge technology. Whether you join us in Madrid or Barcelona, you can make a tangible impact within a global biopharmaceutical company that invests in your future. Join a talented global team that's powering AstraZeneca to better serve patients every day.

Success Profile

Ready to make an impact in your career? If you're passionate, growth-orientated and a true team player, we'll help you succeed. Here are some of the skills and capabilities we look for.

Diverse collaborators

This is a speak-up culture that values collaboration. You’ll proactively bring your unique perspectives, experiences and skills to the table and seek the same from others. With our international team composition and the need for fast-paced collaboration, you’ll always be building new connections with colleagues.

Cutting-edge innovators

When you join us, you’ll be part of a team that embraces digital technology and data to transform the way we work and the work we do. Every day, you’ll help make history, empowered to ignite your creativity and build something enduring.

Resilient trailblazers

Here, the answers aren’t always available. So, you’ll need to bring a fearless, self-starter mindset to navigate uncharted territories. You’ll harness your ceaseless energy to discover and make the necessary connections with colleagues to shape the future and achieve maximum impact.

Agile movers

Seize ownership and excel with autonomy to enjoy the constant rush of ground-breaking discovery. Your ability to anticipate sudden shifts and adapt swiftly will prove critical as you make your mark in an environment that rewards initiative and resilience.

Responsibilities

Job ID R-213068 Date posted 11/13/2024

Location: Barcelona (on-site)

Introduction to role

The Global Market and Access Pricing team at AstraZeneca is establishing a new Centre of Excellence for HTA Statistics and Modelling Science at our global hub in Barcelona. This initiative aims to meet the needs of our expanding pipeline and the evolving external environment. We have exciting opportunities for experienced, applied HTA methodologists and health economic modellers to join our HTA and Modelling Science (HMS) team at either a Director or Lead Level. Our team covers a diverse range of therapeutic areas including Cardiovascular, Renal & Metabolism, Respiratory & Immunology, and Vaccines & Immune Therapies.

As part of a multi-disciplinary group, including HTA statisticians, payer evidence experts, and market access specialists, you will help shape the payer environment by creating and delivering high-quality health economic models. These models will unlock the potential of our life-changing medicines for patients around the world.

Accountabilities

In this role, you will be responsible for implementing HTA methodology and applying your up-to-date hands-on modelling expertise to deliver high-quality, transparent, and fully validated health economic models that meet the requirements and expectations of HTA agencies. This will support patient access to our innovative medicines. With the growing use of HTA, including the upcoming Joint Clinical Assessment in Europe, you will play an important role in shaping our approach. By being at the forefront of methodology and innovation in the field, you will help position the Centre of Excellence for HTA Statistics and Modelling Science as a collaborative, reputable, and trusted organisation among HTA, policy, and academic stakeholders. Development of our people is of utmost importance to us. As part of our new Centre of Excellence, there will be opportunities to learn and further develop skills, as well as spread your knowledge and increase the overall capabilities in the organisation.

For our Director role, you should have:

  • Leadership and strategy setting on HTA modelling and simulation (including indirect treatment comparisons, utility analyses, survival analysis, treatment switching, and other advanced analytics used for HTA and wider market access) across different indications.
  • Significant experience of hands-on modelling of patient level simulations, dynamic models, application of risk equations, parametric survival techniques, and Bayesian analyses, among others.
  • Act as subject-matter expert to unlock modelling challenges and propose methodologically sound, pragmatic, and agile solutions to the team.
  • Develop global standards, guidelines, best practice, and metrics within the team. Lead quality assurance on the implementation of accepted methods for modelling and full validation of health economic models prior to submissions to HTA bodies or scientific journals.
  • Develop and maintain an external network of experts and participate as an expert in collaborations to drive new and innovative HTA methods.
  • Expert knowledge and ability to develop end-to-end decision-analytic models, such as cost-effectiveness or budget impact models fit for submission to reimbursement agencies.
  • Significant experience modelling in Excel and creation of VBA codes.
  • Expert knowledge of global HTA systems and how to adapt models to their varying requirements.
  • Excellent verbal and written communication skills to present to various audiences and develop technical documents like model protocols or model reports and engage with HTA bodies to address model-related queries.
  • Excellent collaboration and interpersonal skills to be able to integrate in a Global cross-functional matrix to deliver objectives and ensure alignment with relevant internal and external stakeholders.
  • Significant experience interpreting clinical data and collaborating with statisticians to deliver trial analyses required to parameterise health economic models.
  • Strong understanding and experience of the methods and application of indirect treatment comparisons in health economic models.
  • Degree in relevant field such as quantitative social sciences (e.g. economics, health economics, health services research), mathematical sciences (e.g. mathematics, statistics, operations research, engineering) or equivalent quantitative skill demonstration (e.g. through development in the workplace).

Why AstraZeneca?
Here we are committed to making a difference. We have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

At AstraZeneca, we play a critical role in making our pipeline accessible to patients. Being a research-driven enterprise means there's always something new to work on; new indications and securing access for new medicines to reach even more patients in need. Our knowledge of patients, combined with our forward-looking mindset and innovations, helps us spot opportunities, get involved earlier, and approach access sustainably. We thrive on autonomy while collaborating across functions and regions, ensuring that our scientific innovations become a reality by securing the right access.

Join us on this fantastic journey as we reimagine the way Market Access is done. Apply now!

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

10000554 G CDHE

Reasons to Join

Thomas Mathisen

There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.

Sales Representative Oslo, Norway

There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.

Christine Recchio

Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.

Sales Representative California, United States

Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.

Stephanie Ling

There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.

Sales Representative Petaling Jaya, Malaysia

There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.

What we offer

We're driven by our shared values of serving people, society and the planet. Our people make this possible, which is why we prioritise diversity, inclusivity, balance and sustainability. Discover what a career at AstraZeneca could mean for you.

An award-winning company

We're passionate about being a great place to work, and 84% of our employees would recommend us as an employer. We've been recognised as a Top Employer in Spain, an EFR Family Responsible Business, and we achieved third place in Forbes Spain's Top 50 Best Places to Work list.

Inclusive environment

Diversity and inclusion are embedded in everything we do, and our different views, experiences and strengths enrich our culture. There's no salary gap at AstraZeneca, and the number of female employees has increased by four per cent over the last three years. We've also made all positions fully accessible.

Work-life balance

Your wellbeing means a lot to us, and we're here to support you through all of life's ups and downs. That's why we offer an unpaid leave policy, annual leave, reduced-hours timetables and a host of benefits, including a retirement plan, long service award, and health and travel insurance.

Sustainability initiatives

We're committed to harnessing the power of science to become a more sustainable business. We've reduced our carbon footprint by over 9,000 kg of CO2 over the last two years, and we lead the European GoGreen Project, which aims to introduce environmentally friendly options in our fleet of corporate vehicles.

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Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.