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HTA & Modelling Science Lead

Posted date Jan. 21, 2025
Contract type Full time
Job ID R-217823
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Why choose AstraZeneca Spain?

AstraZeneca Spain is a rising force in our global business. With headquarters in Madrid and our global hub in Barcelona, we’ve become an important international centre of excellence in the fight against critical disease. Boasting vibrant universities and business schools, the Barcelona ecosystem is a place where scientists can thrive. We attract a diverse workforce from across the globe, shining a beacon for innovation in a country that’s committed to clinical development.

We invite you to bring your talents to Barcelona where our respiratory medicine R&D and Global Marketing centre offers opportunities in R&D, IT, Commercial and HR. Or join us in Madrid and shape our growth in our BUs (Respiratory, Oncology & CVRM ), and a range of Corporate functions. Additionally, you can find sales roles throughout the country. Together, we’re contributing to a world-leading pipeline of therapeutics and delivering life-changing medicines to patients.

Who do we look for?

Calling all tech innovators, ownership takers, challenge seekers and proactive collaborators. At AstraZeneca Spain, breakthroughs born in the lab become transformative medicine for the world's most complex diseases. Alongside technical expertise, colleagues have the resilience, energy and collaborative mindset to change lanes, work with different teams and start projects from scratch.

Here, diverse minds and bold disruptors can meaningfully impact the future of healthcare using cutting-edge technology. Whether you join us in Madrid or Barcelona, you can make a tangible impact within a global biopharmaceutical company that invests in your future. Join a talented global team that's powering AstraZeneca to better serve patients every day.

Success Profile

Ready to make an impact in your career? If you're passionate, growth-orientated and a true team player, we'll help you succeed. Here are some of the skills and capabilities we look for.

Diverse collaborators

This is a speak-up culture that values collaboration. You’ll proactively bring your unique perspectives, experiences and skills to the table and seek the same from others. With our international team composition and the need for fast-paced collaboration, you’ll always be building new connections with colleagues.

Cutting-edge innovators

When you join us, you’ll be part of a team that embraces digital technology and data to transform the way we work and the work we do. Every day, you’ll help make history, empowered to ignite your creativity and build something enduring.

Resilient trailblazers

Here, the answers aren’t always available. So, you’ll need to bring a fearless, self-starter mindset to navigate uncharted territories. You’ll harness your ceaseless energy to discover and make the necessary connections with colleagues to shape the future and achieve maximum impact.

Agile movers

Seize ownership and excel with autonomy to enjoy the constant rush of ground-breaking discovery. Your ability to anticipate sudden shifts and adapt swiftly will prove critical as you make your mark in an environment that rewards initiative and resilience.

Responsibilities

Job ID R-217823 Date posted 01/21/2025

At AstraZeneca we are dedicated to redefining the future of healthcare by unlocking the power of what science can do for people, society and the planet.  Working here means being bold, thinking big and working together to make the impossible a reality.

Working at AstraZeneca means being entrepreneurial, thinking big, and working together to make the impossible a reality. We are focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we think we can really change the course of medicine and bring big new ideas to life. We continuously forge partnerships that help pursue extraordinary medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.

Typically leads in one or two tumour types in the Health Technology Assessment (HTA) and Modelling Science Team, setting individual medicine/indication strategy, giving to methodology development and application, ensuring high quality analytics for use in global HTA submissions, contributing to global publications and developing in-house simulation and modelling tools.

Typical Accountabilities

  • Develops strategic approach and delivery of HTA modelling and simulation tools for assigned medicine

  • (including network meta analyses (NMA), population-adjusted and standard indirect treatment comparisons

  • (ITC), utility analyses, survival analysis, and other advanced analytics used for HTA and wider market access)

  • High level of interactive communication and influencing cross-functional partners and external customers,

  • understanding the payer and industry perspective to developing and implementing innovative HTA methods

  • and solutions to complex problems.

  • Recognises and applies the value of HTA techniques to inform market access and wider cross functional

  • decision-making

  • Co-develops the HTA & Modelling Science publication strategy for specific tumours, working with Health

  • Economic and Payer Evidence (HEPE) and other cross functional partners, along with authoring publications

  • Provides leadership and input to internal HTA & Modelling science guidance documents

  • Develops the Payer Analysis Plan strategy and analytic approaches to payer questions and challenges

  • Provides input to quality assurance of modelling and simulation work, contributing to global standards, best

  • practice, and metrics

Education, Qualifications, Skills and Experience

Crucial

  • Bachelors’ degree in mathematical sciences (e.g.mathematics, statistics, operations research, engineering) or quantitative social sciences (e.g.economics, health economics, health services research) or similar quantitative skill

  • demonstration

  • Master’s degree in relevant field (as above) or substantial equivalent experience

  • Experience across multiple tumors and products as well as submission and defense in at least one HTA market

  • Shown experience in health economic modelling or similar experience

  • Experience in oncology health economic modelling, survival analysis, utility analyses, and NMAs and Bayesian analyses.

  • Advanced Excel user, including VBA

  • Technical knowledge of the changing HTA requirements globally and how to deliver against these.

  • Strong skills in communication, influencing,handling complexity, decision-making, and how simulation work can impact on wider market access and value communication

  • Ability to operate independently with direction as

    required

Desirable

  • PhD or equivalent experience in a relevant quantitative field

  • Previously worked in Pharma (at a local or global level) with launch experience Experience across multiple HTA systems.

  • Statistical software / programming coding

  • Population adjusted indirect comparisons

  • Treatment switching analysis

Key Relationships

  • Oncology biometrics (statistics and programming)

  • Medical affairs and evidence teams

  • Clinical outcomes assessment team

  • Health Economics & Payer Evidence and wider

  • Oncology Market Access and Pricing (OMAP)

  • community

  • Marketing Company/local affiliate HTA related

  • team

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

50056657 F CDHE Oncology

Reasons to Join

Thomas Mathisen

There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.

Sales Representative Oslo, Norway

There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.

Christine Recchio

Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.

Sales Representative California, United States

Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.

Stephanie Ling

There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.

Sales Representative Petaling Jaya, Malaysia

There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.

What we offer

We're driven by our shared values of serving people, society and the planet. Our people make this possible, which is why we prioritise diversity, inclusivity, balance and sustainability. Discover what a career at AstraZeneca could mean for you.

An award-winning company

We're passionate about being a great place to work, and 84% of our employees would recommend us as an employer. We've been recognised as a Top Employer in Spain, an EFR Family Responsible Business, and we achieved third place in Forbes Spain's Top 50 Best Places to Work list.

Inclusive environment

Diversity and inclusion are embedded in everything we do, and our different views, experiences and strengths enrich our culture. There's no salary gap at AstraZeneca, and the number of female employees has increased by four per cent over the last three years. We've also made all positions fully accessible.

Work-life balance

Your wellbeing means a lot to us, and we're here to support you through all of life's ups and downs. That's why we offer an unpaid leave policy, annual leave, reduced-hours timetables and a host of benefits, including a retirement plan, long service award, and health and travel insurance.

Sustainability initiatives

We're committed to harnessing the power of science to become a more sustainable business. We've reduced our carbon footprint by over 9,000 kg of CO2 over the last two years, and we lead the European GoGreen Project, which aims to introduce environmentally friendly options in our fleet of corporate vehicles.

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Glassdoor logo Rated four stars on Glassdoor

Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.