Diagnostic Senior Scientist

Introduction to role:

This role is based in Barcelona, with an on-site commitment of three days a week. Fluency in English is required. 

Are you an experienced diagnostic scientist eager to apply your skills and bring technical expertise and scientific innovation to develop diagnostics for clinical use? If so, this could be the role for you! AstraZeneca delivers companion and complementary diagnostic assays that match medicines to patients most likely to benefit from them. This approach, known as Precision Medicine, leverages individual characteristics that influence treatment responses. As a Diagnostic Scientist, you will utilize your knowledge of oncology diagnostic technologies, such as Immunohistochemistry (IHC), multiplex IHC, proteomics, and digital pathology, to provide scientific and technical expertise. You will drive innovative diagnostic approaches within AstraZeneca’s clinical portfolio through strategic partnerships with leading diagnostic companies and laboratory-based science delivery.

Accountabilities:

• Deliver laboratory-based diagnostic science and innovation projects with a focus on multiplex IHC and proteomics, collaborating closely with cross-functional teams.
• Build and maintain knowledge of current and emerging technologies in diagnostics for the AZ oncology portfolio, identifying opportunities for innovation and collaboration.
• Develop innovative diagnostic science proposals across core therapeutic areas.
• Evaluate the performance of novel diagnostics through feasibility studies and laboratory-based science, adhering to timelines and budget.
• Provide scientific and strategic feedback into precision medicine approaches for diagnostic and drug product teams.
• Ensure all activities align with AstraZeneca's Code of Conduct, supporting policies, standards, and procedures, including compliant management of Budget, Safety, Health, and Environment.

Essential Skills/Experience:

• Masters / PhD or equivalent experience in a relevant subject
• Record of delivery in a scientific capability, including peer-reviewed publications
• Expertise with IHC and one or more of the following technologies (for example, but not limited to: digital pathology, multiplex proteomics, NGS, PCR & imaging)
• Excellent knowledge of current technology trends in oncology diagnostics and precision medicine
• Experience of working with external partners or collaborators (ideally academic investigators and diagnostic companies)
• Ability to communicate with cross-functional stakeholders for project updates through oral presentations and progress reports

Desirable Skills/Experience:

• Experience developing tissue-based diagnostic assays in a regulated environment e.g. under In Vitro Diagnostics development standards or within a CAP/CLIA laboratory
• Experience of leading projects within a diagnostic or drug development organisation
• An understanding of drug and companion diagnostic assay co-development and commercialisation and experience working in early and/or late phase projects
• Demonstrable experience of analytical diagnostic assay validation, use in a clinical testing setting and/or delivery of regulatory submission
• Good computational and data analysis skills enabling automated/semi-automated analysis of large datasets (e.g. using software and programming languages such as R, Python, knime or equivalent)
• Knowledge of requirements related to handling of Human Biological Samples

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca is a place where you can be empowered to act fast on smart risks! With one of the broadest and deepest Oncology pipelines in the industry, there are countless opportunities to work with new drugs and discover what's next. We foster a mindset of courage, empowering everyone to innovate and work at pace. Collaborate globally with top experts across diverse functions for multidisciplinary learning. Our commitment to patients drives us to make meaningful differences worldwide.

Ready to make bold moves in the fast-paced field of Oncology? Apply now!

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.