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Oncology Cell Therapy Unit

Careers at the forefront of Oncology R&D in the newly formed Cell Therapy Unit

AstraZeneca is a leader in Oncology with a global footprint. We are following the science to understand cancer and all its complexities to discover, develop and deliver life-changing treatments and increase the potential to save the lives of people around the world.

Within Oncology R&D, AstraZeneca, we are investing in our internal capabilities to help us realise our ambition to become leaders in the delivery of next-generation cellular therapies. Leveraging historical expertise in biologics engineering, gene editing and immunology across solid and haematological malignancies, we are uniquely positioned to develop cutting-edge technologies to advance cell therapies in cancer treatment.

Our global, multi-disciplinary oncology cell therapy team is a dynamic group of scientists and physicians with a passion for advancing cellular therapy research and development.

Value of joining the AstraZeneca oncology cell therapy team

  • Opportunity to be part of building an innovative cell therapy pipeline
  • AstraZeneca is a leader in Oncology and has a track record of delivering great products to the market
  • Direct support from senior leadership and potential for high-impact roles
  • Founding members will play a key role in shaping the culture of the unit and establishing the ways of working
  • Commitment to follow the emerging science
  • Nimble and agile working model while still enjoying the benefits of support from the broader organisation.

AstraZenea's ambition in Cell Therapy: Advancing today’s cell therapies and developing tomorrow’s cancer breakthroughs

The promise of Adoptive Cellular Therapies (ACTs) is based on the knowledge that immune cells are the frontline in the attack against foreign and/or harmful entities in the body. A hallmark of cancer is its ability to evade the immune response by signalling suppression of immune cells. Patient derived immune cells that are expanded and genetically modified before being reintroduced to patients are aimed at harnessing the full potential of immune cells to recognise and attack tumour cells by driving a new immune response.

AstraZeneca is building a cell therapy portfolio that aims to empower and equip T cells, to more effectively fight cancer. We are building on the work already done in blood cancers, where the efficacy potential of chimeric antigen receptor expressing T cells (CAR-T cells) has been demonstrated in some haematological malignancies. Our research teams are exploring new ways to target and arm CAR-Ts to increase their effectiveness in solid tumours by overcoming the immune-suppressive tumour microenvironment.

With an eye to the future, AstraZeneca is working towards next generation  cell therapies, where physicians could potentially select from a library of patient-ready therapies already developed from the cells of healthy donors.

What AstraZeneca is looking for: 

  • We are currently recruiting talented, driven and passionate individuals
  • Team players who actively contribute to create a great place to work
  • Driven to always putting patients first and by the curative potential of cellular therapies
  • Ambitious to contribute to being at the forefront of innovative science.

Why join AstraZeneca’s team?

  • AstraZeneca’s mission is to transform innovative molecules into medicines that change lives.
  • AstraZeneca is a leader in Oncology and has track record of delivering great products to the market
  • We always put patients first and are driven by the science
  • Great place to work - We play to win and have fun in the process
  • Direct support from senior leadership and potential for high-impact roles
  • At the forefront of innovation and science that can maximise the curative potential of cellular therapies
  • For researchers, AstraZeneca nurtures innovation and provides freedom to bring meaningful ideas to the clinic.

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