Our Commitment to CVRM Innovation
The immense impacts of CVRM diseases on people, society and our planet are growing, yet these diseases remain underdiagnosed, undertreated and their interconnections under-recognised. Our ambition is to enhance care to improve outcomes for the millions of people who are living with the complexities of CVRM diseases, to intervene early to protect vital organs, slow or stop disease progression, and one day even cure these often debilitating, progressive and life-threatening conditions. Through understanding the interconnections of these diseases, where a condition in one organ system can negatively impact another, we are able to extend the use of our existing medicines and build one of the world’s broadest, deepest and strongest CVRM pipelines.
By 2030, we aim to be leading the world in CVRM therapies, helping to change the course and reach of medical practice.

Be a part of the team exploring the next frontier of what science can do for chronic disease.
We are pioneers – pushing the boundaries of science to deliver life-changing medicines, transform care for billions of people living with chronic diseases and deliver long-lasting immunity. Beyond our medicines, we know there are more ways we can help patients. We help build and strengthen American healthcare and innovation ecosystems, co-create solutions that change medical practice, and translate cutting-edge science into real-world impact across the full patient experience. Guided by pioneering leaders, every step we take starts with patient need. We take smart risks, challenge convention and reinvent what’s possible.
AstraZeneca is a place for bright minds and visionary doers. We bring together diverse perspectives to move with agility, learn from failure and grow – supported to stretch within and beyond our roles.
If you’re ready to break new ground and help shape a healthier future in the US, AstraZeneca is where you belong.

Why join AstraZeneca US BioPharma

Key reasons to join Oncology Business Unit

Our focus areas

Our people
Built on an impressive legacy in CVRM, we are uniquely positioned to build a healthier and longer future for people with CVRM diseases. Our team of over 1,000 people spans more than 23 functions including early and late R&D, medical and commercial.
We’re proud to foster a culture of constant exploration, questioning and challenging to find ways to do things differently, and to make a positive difference in patients' lives.
Our pipeline
With more than 25 therapies and therapy combinations in our early-to-late stage pipeline, we seek to bring real science and development to combatting life-threatening conditions. Our first-class scientific research today is setting the stage for our pioneering approach in the fields of disease regression and organ regeneration, putting us a step closer to making science fiction a reality.
Collaboration in CVRM care
We are proud to be working with healthcare professionals, patients, governments and policy makers to improve access to healthcare, and remove barriers to diagnosis and optimal treatment. Our goal is to fundamentally change how CVRM diseases are detected, diagnosed and treated to accelerate medical practice change and make a difference for patients.


A career in the BioPharmaceuticals Business Unit at AstraZeneca has purpose, meaning and impact. Your work and contributions will help enhance the quality of life for millions of patients around the world living with Cardiovascular, Renal, Metabolic (CVRM), Respiratory, Inflammatory and Autoimmune (RIA) diseases.
– Ruud Dobber, EVP Biopharmaceutical Business Unit
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