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Scientist/Senior Scientist, Immunology Cell Therapy Discovery

Location Waltham, Massachusetts, United States Job ID R-242732 Date posted 07/01/2026

ROLE: Scientist/Senior Scientist, Immunology Cell Therapy Discovery

Accountabilities

  • Design and complete laboratory-based experiments with high consistency and performance
  • Analyze data, present findings to team, and propose next steps
  • Work collaboratively within the immunology cell therapy discovery team and cross-functionally across AstraZeneca
  • Maintain a high standard of ELN documentation 

Essential Skills/Experience :

  • Education:
    • Scientist: BS with a minimum of 5 years’ experience in Immunology, Cell Biology, Molecular Biology, or related field OR a MS degree with a minimum of  3+ years of relevant industry/academic experience.
    • Senior Scientist: PhD with 0–3+ years post PhD or BS/MS with 6–10+ years demonstrated impact in cell therapy discovery.
  • Immunology expertise: Handson experience with human primary immune cells, especially T cells, including isolation, activation, expansion, and functional assays.
  • Flow cytometry: Confirmed ability to design multicolor panels, troubleshoot artifacts, set gates/controls (FMO/Isotype), and perform thorough data analysis using FlowJo, PRISM, and/or OMIC.
  • MSD/ELISA: Experience running and troubleshooting MSD/ELISA assays with strong understanding of assay performance metrics and statistics.
  • Molecular cloning and lentivirus: Competence in construct design, cloning, LV packaging, concentration, titration, and safe handling per BSL2.
  • Data difficulty: Strong experimental design, statistical analysis, and clear communication in presentations and reports.
  • Teamwork: Ability to work in a fast paced, collaborative environment, managing multiple priorities and delivering on timelines. 

The annual base pay for this position ranges from $87,200 - $130,800. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

NOTE: This role is based out of our scenic Waltham BioHub and will move to our new R&D center in Kendal Square by the end of 2026.  

Compensation Pay Range:

87,200.00 - 130,800.00 USD Annual

The annual base pay (or hourly rate of compensation) for this position is outlined above. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

08-Jan-2026

Closing Date

21-Jan-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value our people.