Medical Affairs Manager

Position: Medical Affairs Manager (Transthyretin amyloidosis ATTR and CV Early Assets)

Location: Pancras Square

Competitive Salary & Benefits

Join us on our mission to transform care in the UK in partnership with the healthcare system. As part of the Cardiovascular, Renal & Metabolic (CVRM) Medical Affairs team, you will be accountable for workstreams that advance clinical practice, improve patient outcomes, and promote health equality. You will also be accountable for establishing and maintaining AZ’s position as the scientific leader and partner of choice, delivering high-level external stakeholder engagement with expert clinicians, professional societies and patient groups.

Accountabilities

In this role, you will contribute to the development and implementation of world-class medical and brand strategy across ATTR and CV early assets. You will support the launch and rapid patient access of innovative medicines in the CVRM space. You will also support the development and implementation of quality improvement initiatives which are scalable and impact clinical practice. Collaborating with key external stakeholders to advance clinical practice, you will maintain AstraZeneca’s position as the scientific leaders and partners of choice. You will also support evidence generation and dissemination initiatives which have impact on clinical practice. Collaborating with cross-functional teams to influence system policy and clinical guidelines, you will build and support internal scientific expertise and capability on TA and product knowledge. You will provide expert medical input into regulatory submissions/variations and national and regional market access initiatives.

Essential Skills/Experience

• Science degree - BPHARM, BSc, MBBS or equivalent
• Proven experience of being innovative and thinking creatively; eg. changing clinical pathways for benefit of the patients
• Proven ability to partner with senior external stakeholders, including clinicians, professional societies and patient groups
• Strong communication skills and project management experience
• Evidence of effective team working and accountability
• Proven track record of successful execution of strategically aligned plans

Desirable Skills/Experience

• Clinical or medical affairs experience in cardiovascular/metabolic diseases, preferably amyloidosis and/or dyslipidaemia
• Medical affairs experience in UK
• Higher bioscience degree (master’s, MD or PhD)
• Familiarity with UK pathways in cardiovascular disease

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn't mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca's Biopharmaceuticals Business Unit, you'll be at the forefront of our mission to shape the future of healthcare. There's so much opportunity here as we continue to grow - no better place to improve patients' lives and develop with AstraZeneca. A critical part of AstraZeneca's success, we provide medical leadership across the whole product lifecycle - from advising on Research & Development investment decisions, to leading pre-launch scientific efforts and accelerating evidence-based healthcare changes in the real world.

Be scientific ambassadors for AstraZeneca! Be equipped with the knowledge you'll need to keep pace with rapid complex science and the latest changes in medical practice and therapeutics worldwide. Here we have both medical expertise and business acumen, understanding which products are launching and the science behind each of them. It means we can be confident in our role as strong ambassadors of our science-led enterprise.

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

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Interested? Please apply by submitting your CV by COB 10th February 2026

Date Posted

27-Jan-2026

Closing Date

10-Feb-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.