Scientist - Conjugation and Purification
About the role
At AstraZeneca,we'reembarking on an exciting new frontier in medical science – the quest to extend humanhealth span. Our newly formed Aging Research Group is at the forefront of this groundbreaking initiative, aiming to develop innovative therapeutics that not only add years to life but life to years.
Main Duties & Responsibilities:
In this role, you will be part of a team of highly skilled and passionate individuals responsible for innovating and generating the best in class of antibody drug conjugates for various therapeutic areas. We areseekinga highly motivated conjugation scientist with a preferred background in drug discovery. Exciting opportunity to learn and contribute to multi-disciplinary drug development.
Conjugation,purificationand characterization ofprecursors for radio-conjugates(RC)and ADCusing multiple validated methodologies
Development and optimization of novel conjugation methodologies to improveRCand ADCproperties
Radiolabeling of RCfor in vitro and biodistribution evaluations
Collaborate and work with a diverse group of scientists across multiple therapeutic areas, chemistry, and process development to ensuretimelyprogress in research projects and drive technological innovations
Partner with colleagues on laboratory maintenance, including maintenance of equipment and lab safety.
Education & Experience Requirements:
Bachelor's or Master'sdegree in biotechnology,Pharmaceuticals Sciences,Chemical Biology, Biochemistry, Chemistry, or other relevant scientific field with3+ years (BS degree) or0-1years (MS degree) of relevant experience.
Required Skills:
Hands-on experience and knowledge of protein purification using HIC, IEX,SECand affinity chromatography. Experience with GE AKTA FPLC preferred.
Working knowledge of characterization using analytical techniques like Hydrophobic Interaction Chromatography (HIC)-HPLC, Size Exclusion Chromatography (SEC), Liquid chromatography–mass spectrometry (LC-MS), Ion-Exchange (IEX), Reversed Phase (RP)-HPLC, etc.
Proven ability to work independently, effectively plan and organize work activities and prioritize task completion to meet project deadlines
Demonstrated experience inoptimizing/troubleshootingprotocols with a problem-solving mindset andmaintainsa detailed laboratory notebook
Desired Skills:
Demonstrated hands-on experience in the generation ofRC and ADC.
Experience withradiochemistry and related assays.
Excellent written and verbal communication skills and effective presentation of complexscientific datatocross-functional and senior management.
The annual base pay for this position ranges from $87,200 - $130,800. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Compensation Pay Range:
87,200.00 - 130,800.00 USD AnnualThe annual base pay (or hourly rate of compensation) for this position is outlined above. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Date Posted
08-Jan-2026Closing Date
30-Jan-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
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