Assoc Princ Scientist Bioscience

At AstraZeneca, we turn ideas into life changing medicines. Working here means being entrepreneurial, thinkingbigand working together to make the impossible a reality.We’repassionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring bignew ideasto life.

AstraZeneca’s vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and toultimately eliminatecancer as a cause of death. A broad pipeline of next-generation medicines is focused principally on four disease areas - breast, ovarian, lung and hematological cancers.

We areseekinga highly motivatedAssociate PrincipalScientist with aproventrack recordofscientific excellenceand project leadershipinoncology researchto join our antibody-drug conjugates(ADCs)portfolioteamwithin the Early Oncology Discovery groupin Gaithersburg, MD USA.  Asan Associate PrincipalScientist,youwill leada team focused onbringing new ADC projects into the portfolio and advancing them through all stages of pre-clinicaldevelopment.

You will bring your theoretical and practicalexpertisetolead pipeline projects,establishingprogramprioritiesandworkingwith a cross-functional team todeliverpre-clinicaldatasetsto support pipeline progression. You willrepresentthe team in front of governance committees and will present program updates at other internal forums.You willalso make intellectual contributions to programs across the ADC Portfolioand be anengaged people manager and mentor.

Main Duties and Responsibilities

• You will be expected to serve asOncologybiology leadfor one or more pipeline programs, working collaboratively with cross-functional teams to ensure thetimelygeneration and dissemination of critical program datato enable milestone progression decisions.  

• You will help set programstrategy, andwillberesponsible forthe delivery ofkey pre-clinical data that support astrongbiological rationale for program progression.

• Youwill be expected to work independentlyandcollaboratively,andeffectively planand organize work activities and prioritize task completion for yourself and direct reports

• You willmanageand mentora team of direct reports

• As a highly organized, self-motivated individual with a strong background incancer biology,you will stay up to date with relevant technical and intellectual scientific expertise in tumor biology and cancer modelling, particularly as it relates to antibody drug conjugates,and have a genuine passion for this field of research.  

Essential Requirements

• Ph.D. with 5-10 years of research experience orMaster’sdegreewith 8+ years within the pharmaceutical industry and clear demonstration of solving challenging problems in drug discovery

• Demonstrated ability to lead cross functional project teams.

• Demonstrated management and leadership skillsand a passion for mentorship

• Strong knowledge ofsolid tumorcancers, in-vitro and in-vivo pre-clinical models of cancer,cell biology, molecular biology, and/or biochemistry in the context of cancer biology, witha strong desireforcontinued learning.

• Works independently todesign andconductkeyexperimentsto support program progression.

• Excellentverbal and writtencommunication,presentation, and interpersonalskillsandevidence of delivery in a team-oriented, collaborative environment.

• A proventrack recordof productivity, asdemonstratedby scientific publications in high quality peer-reviewed journals.

• Ensures own work, and work of peers, is compliant with Safety, Health, and Environment standards and all other relevant internal AstraZeneca standards and external regulations.

Desirable Requirements

• Prior experience in the biopharmaceutical industrypreferablebut notrequired.

• Prior experience with antibody-drug conjugates preferable but notrequired

When we put unexpected teams in the same room, we unleash bold thinking with the power to encourage life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our outstanding and ambitious world.

The annual base pay for this position ranges from $142,377.60 - $213,566.40 USD Annual. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles).