Production Technician I/II, Downstream -Nights

Our Frederick Manufacturing Center (FMC) creates life-changing medicines for people around the world and has been recognized by our local community as being a Top 50’ Business in Frederick and awarded Frederick County’s ‘Best Place to Work’. This distinctive biologic manufacturing facility, with over 800 employees, makes a direct contribution to treating people with cancer, respiratory and autoimmune conditions across the globe.  We work hard to deliver life-changing medicines to patients, and we take time to have fun and celebrate our accomplishments. From catered site festivities to competitive events, community outreach activities, environmental and wellness showcases and team-building functions, we take time to recognize our achievements and celebrate our diversity.  We are dedicated to creating a culture of inclusion and collaboration and are committed to continuous learning by offering ongoing skill building and training for our staff.  Fueled by our aspiration to deliver accelerated growth for our company and to make people’s lives better, there’s never been a more exciting time to join the team and shape the future of AstraZeneca Operations.

Are you ready to break new ground and leave a collective legacy? As a Production Technician I at AstraZeneca, you will have the opportunity to play a pivotal role in evolving our Supply Chain. You will be operating upstream / downstream / central services processing equipment according to established SOPs. This is your chance to be part of a team that's reimagining how we do things and creating a collective legacy.

12 hour shift - 2-2-3 (2 days on, 2 days off, 3 days on, 2 days off)

Accountabilities:
The Production Technician I spends most time on the shop floor executing assigned tasks under supervision while learning and applying cGMP, quality and SHE requirements. Core responsibilities include equipment setup/takedown, cleaning, routine maintenance, completing electronic and paper records (MES), escalating deviations, supporting area ownership and participating in basic continuous improvement activities.

Technical Skills — Production Knowledge, Process Execution, Quality, and Safety Health & Environment

• Basic Process Knowledge: Demonstrates foundational understanding of SOPs, process flows and critical operational parameters; recognizes upstream/downstream dependencies and impacts.

• Process Execution & Documentation: Executes routine production tasks (solution prep, basic cell culture/support tasks, formulation and housekeeping) per SOPs, MPRs and SPRs; completes accurate records in MES to ensure traceability.

• Equipment Operation & Maintenance Support: Supports setup, takedown, cleaning and routine maintenance of equipment under supervision; follows qualification requirements and escalation pathways.

• Quality, SHE & Risk Awareness: Learns and follows GMP, Quality and SHE protocols; identifies and reports unsafe conditions and quality deviations; participates in safety/investigation activities as required.

• Area Ownership & Lean Fundamentals: Supports designated area ownership standards and basic lean practices to maintain a safe, orderly work area and improve local efficiency.

Business Skills — Data Base Thinking, Digital Fluency and Work Planning Execution

• Data Awareness: Uses available data and MES outputs to complete assigned work; records observations and flags anomalies for review.

• Digital Familiarity: Embraces and learns digital tools used in the area; participates in digital adoption and training activities.

• Work Planning & Execution: Manages and prioritizes assigned daily tasks with supervision; completes work on time with attention to detail and communicates status proactively.

People Skills — Communication, Adaptability, and Leading Self

• Communication: Communicates clearly and concisely with peers and Managers; shares updates and escalations in a timely manner.

• Adaptability & Learning: Demonstrates a positive, “can do” attitude; accepts feedback and applies coaching to improve performance.

• Leading Self: Takes responsibility for completing assigned tasks, follows instructions, and complies with Company values and safety requirements.

Additional Responsibilities and Accountabilities

• Participate in initial qualification and on‑the‑job training programs.

• Support area housekeeping and DAO standards.

• Other duties as assigned.

• Conduct activities and interactions consistent with Company values and in compliance with the Code of Conduct and supporting Policies and Standards relevant to your role. Complete all required training on the AZ Code of Conduct and supporting Policies and Standards on time. Report potential issues of non-compliance.

Essential Skills/Experience: Production Tech I

- 0-1 yrs experience with High School Diploma
- Ability to work independently or in collaboration with others on assigned tasks
- Ability to comply with cGMP standards
- Must possess computer skills

- Ability to follow instruction and directions

Essential Skills/Experience: Production Tech II

- 0-1 years experience with Bachelors, >1 year with Associates, >2 years with High School Diploma

- Ability to work independently or in collaboration with others on assigned tasks

- Ability to follow cGMP standards

- Must possess computer skills

- Ability to follow instruction and directions

- Prior experience with aseptic/cGMP standards

-Prior experience in Bioprocessing work environment/systems/equipment operation

Desirable Skills/Experience:
• BS/BA degree preferred
• Degree in STEM field
• Prior experience or exposure with aseptic/cGMP standards and environment 

At AstraZeneca, we are driven by the challenge to stay ahead in rapidly changing markets. We continuously seek new and better ways to deliver medicines all the way to our patients. Our resilience helps us thrive as we innovate and evolve. We foster a safe and positive space where ideas are welcomed and rewarded. If you are self-driven, thrive at pace, continuously learning, and proactively taking on more, then this is the place for you.

Ready to make an impact? Join our Operations team today and contribute to life-changing medicines. Apply now!

The annual base pay (or hourly rate of compensation) for this position ranges from $56,0720.00 to $84,108.00 Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.