Global Clinical Head, Respiratory

The Global Clinical Head (GCH) is the most senior medical scientific expert on an asset/product/indication team and is a core member of the Franchise Team (if applicable) and/or the Global Product Team (GPT). 

This role will report to the Vice President Clinical Respiratory. 

This person will be accountable for all clinical scientific aspects of the product/asset, including the benefit/risk of a product and/or asset as well as the scientific strategies for clinical components of the Target Product Profile (TPP), Target Product Claim (TPC), Clinical Development Plan (CDP), Clinical components of regulatory documents and core labelling texts. 

Provide clinical and medical expertise input into overall project strategy. Will have accountability for the clinical deliverables i.e. clinical studies, clinical components of regulatory submissions etc to time. 

Serve as the single point of contact for TA-Heads and R&D leaders for clinical and scientific components of the product and/or indications. 

Essential for the Role

• An MD, or other equivalent medical degree from an accredited university with specialty training in Respiratory or related area. 

• Relevant experience within the respiratory space, including late-phase drug development experience. 

• Demonstrated deep clinical and research expertise in appropriate disease area 

• Significant hands-on late phase clinical drug development experience. 

• Developed/delivered multiple complex and large studies (e.g., including but not limited to multinational outcome studies). 

• Scientific credibility internally and externally. 

• Demonstrated success in influencing functions outside of clinical and across geographies. 

• Experience of benefit/risk assessment and creating patient risk management plans. 

• Experience of global regulatory submissions and interacting with major regulatory agencies. 

• Demonstrated ability to successfully lead, coach, and mentor other physicians/scientists. 

• Proven teamwork and collaboration skills in a global setting. 

• Credible in scientific and commercial environments. 

• Fit for purpose business acumen, and insight into payer and reimbursement hurdles globally 

• Line management experience. 

Desirable for the role

• Global external awareness within the therapeutic area. 

• Global regulatory awareness. 

• Ability to travel nationally and internationally. 

• Experience in several organizations and geographic locations 

• Experience of working with Market Companies to deliver studies/projects. 

• Experience of clinical/commercial interface. 

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. 

This means we’re opening new ways to work, pioneering groundbreaking methods and bringing unexpected teams together. 

Date Posted

10-Aug-2026

Closing Date

16-Aug-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.