Senior Global Medical Affairs Leader, Obesity

AstraZeneca is advancing a tailored approach to Obesity and Weight Management, uniting science, medical and commercial excellence to deliver durable outcomes, reduce cardiometabolic risk and protect organs. Our pipeline is moving with purpose and includes next generation oral and injectable therapies that prioritises tolerability,durabilityand quality of life.Are you ready to be at the forefront of medical innovation? As theSeniorGlobal Medical Affairs Leaderfor ObesityandRelated Complications,you'llplay a pivotal role in shaping the future ofobesity care. This is your chance to use yourexpertiseto make a real impact on patients' lives. Join us in our mission to transform the patient journey, from prevention to diagnosis, and beyond.

Accountabilities

In this dynamic role,you'llbe responsible forproviding medical leadership across the entire product lifecycle.You'lladvise on Research & Development investment decisions, lead pre-launch scientific efforts, and accelerate evidence-based healthcare changes in the real world. Your networking and influencing skills will be key as youfacilitatecross-functional collaboration and drive innovation. Are you ready to take on this challenge?

Role Summary:

Reportingto the MedicalHeadofWeightManagement, the Senior GMAL is ahighlyexperiencedMedical Affairsleaderwithproven vision andimpact.Thisindividualdevelopsandleadsboldmedicalstrategieswithintheobesityandcardiorenal-metabolicoutcomestherapyarea(specificallyMASH,heartfailureand CKD),expertlyguidingcross-functionaland cross-regional teams todeliverandexceedambitiousgoals. The SeniorGMAL’sinfluenceisenterprise-wide—shapingglobalmedicalagendasthroughGlobal Medical Team, Global Product Team, andDiseaseArea Teamleadership, anddeeppartnershipwithMedical and Commercialfunctionsin marketsand regionsworldwide.

Thisroledemandsaleaderwhochampions innovative,disruptivethinking—identifiesandshapesbreakthroughopportunities,reimaginesmarketdynamics, andaccelerateshigh-impactevidencegeneration andmedicalchangeinitiatives. The Senior GMALnavigatesand transformshealthsystems, leverages digital andadvancedanalytics, drivesstakeholderengagement, andensuresAstraZeneca’sscienceleadsexternallyandinternallythroughworld-classmedicalevidenceandstrategicpartnerships.

Expectations of a Senior GMAL include:

• Strategy& Transformation: The Senior GMAL designs andleadsthe implementationofproductanddiseaseareastrategies, aswellasambitiouspracticechangeinitiatives, at a globallevel.Thisrequiresadeepunderstandingofhealthcare systempathways,regulatorylandscapes,market access, andcompetitivedynamics. The Senior GMALconsistentlydelivers innovative,disruptivesolutions toshapemarkets,challengesstatusquothinking, andusesdigitalproficiencytoidentifydata-drivenopportunities,preparingforlaunchandlifecyclemanagement.

• MedicalEvidenceLeadership: SeniorGMALsowntheevidencegenerationstrategy—demonstratingadvancedexperienceinclinicalresearch,interventionaltrials(Phases2–4), and real-worldevidence(RWE) programs.Theyshapeand drivegroundbreakingclinicaltrials,registries, and RWE studiesalignedwithbrand, access, andpractice-changingobjectives.Theyguide theoptimisation,communication, andstrategicroll-outofdataacrossscientificplatforms,ensuringAstraZeneca deliversdifferentiatedevidencethatsupports theneedsofregulatory,payer, and healthcareproviders. Clinical research, patientoutcomesexpertise, anddeepunderstandingoftreatmentprotocolsunderpintheirabilitytoaddressevolvingevidencerequirements.

• AdvancedScientific& DigitalEngagement: The Senior GMALblendsscientificexpertisewithstrong digitalacumen.Theyleveragedigitalhealthtools,advancedanalytics, and dataplatformsto transformevidencecommunication,personalizestakeholderengagement, andenhancepatientoutcomes.Theyarethe voiceofmedical—craftingcompellingnarratives,drivingdigital disseminationofevidence, andensuringaccurate,impactful, andcompliantscientificcommunications.

• GuidingandInfluencingStakeholders:Withsignificantexpertiseininternalandexternalengagement, the Senior GMALbuildsandsustainspowerfulrelationshipsacrossthe healthcareecosystem—includingglobal and regionalKOLs,professionalsocieties, regulators,payers, patientorganizations, digitalinnovators, andhealthsystems.Theircredibilityandinfluenceenablethemtomobilizesupport formedicalstrategy,evidencegeneration, and healthcarechangeinitiatives.Theymentor andguide cross-functionalteams,championingscientificleadershipandstrategiccollaboration.

• RegulatoryInsight&Compliance: The Senior GMALpossesseskeenregulatoryunderstandingandensuresclinicaltrial andevidencegenerationinitiativesaredesignedforbothscientificandregulatorysuccess.Theyanticipateevolvingregulatoryandpayerrequirementsforevidence,ensuringhighquality,compliantdata generation andcommunicationateverystage.

Essential for the role:

• Doctoral-level degree (MD, PhD, PharmD) 

• Master’s degree with at least 5 years of experience in the pharmaceutical industry (Medical, Marketing, R&D, Market Access), or extensive experience within a health system (clinical, pharmacy, pathway design, etc.).

• Demonstrated leadership in complex, global healthcare environments, including leading franchise/TA business in key markets, driving brand performance, and managing large, diverse teams.

• Significantexpertiseand strategic insight into healthcare system pathways, regulatory landscapes, market-shaping, and external stakeholder engagement.

• Strongtrack recordof internal and external network building, collaboration across geographies and matrix teams, and effective mentoring of junior colleagues or peers.

• Digitalproficiency,leveragingdigital health tools and data platforms to advance evidence generation and communication.

• Deep understanding of patient care pathways, evolving treatment protocols, scientific literature, and contemporary approaches to healthcare transformation.

• Proven ability to guide, influence, and align diverse stakeholders—including thought leaders, regulatory bodies, patient groups, and payer organisations.

Desirablefor the role:

• Clinicalexperience inobesity, PCP,heartfailureand/or CKD

• Experience with the USA health care system

• Recognisedexpertisein the relevant or related therapeutic area, oftenevidencedby a history of clinical practice, research leadership, or significant external engagement.

• Advanced experience designing, leading, and interpreting clinical research programs, including pivotal clinical trials (Ph2–Ph4), practice-changing RWE studies, and implementation of innovative evidence generation approaches.

• Broad experience beyond Medical Affairs; for example, prior roles in Marketing, R&D, or Market Access.

• Long-standing relationships with global KOLs, societies, regulators, digital health partners, and innovative healthcareorganisations.

• Track recordof launching new products or indications in multiple, diverse markets (e.g., US, China, EU), and successfully developing and executing global medical strategies.

• Location;Boston, Massachusetts, USA(relocation support provided)

Total Rewards:

The annual base pay (or hourly rate of compensation) for this position ranges from $243,586 to $365,379 Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com.