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Head of Data Science and Advanced Analytics , US Commercial

Location Boston, Massachusetts, United States Job ID R-245098 Date posted 04/02/2026

Are you ready to lead the charge in transforming data into actionable insights? As the Head of Data Science and Advanced Analytics , US Commercial , you'll be at the forefront of setting and executing the vision and strategy for advanced analytics initiatives. This critical position involves using data-driven insights to improve the US Commercial strategy, sales, patient engagement, and market expansion in outstanding and rare diseases. Drive innovation and maximize the impact of data science on business results in one of the world's most dynamic healthcare markets!

You will be responsible for:

Strategic Leadership:

Develop and lead the execution of a data science and advanced analytics strategy tailored to the US Commercial business, with a focus on maximizing field effectiveness, patient identification, customer engagement, and commercial success in rare and specialty disease markets.

Partner with US Commercial leadership and cross-functional collaborators to ensure alignment of analytics priorities. Drive the adoption of AI, predictive modeling, and advanced insights throughout the commercial division.

Operational Management:

Coordinate the Center of Excellence's operations involving data science and sophisticated analytics to support US Commercial objectives. Ensure deliverables are timely and meet high-quality standards. Address emerging needs in the market, payer trends, and evolving competition.

Continuously improve data pipelines, analytical processes, and reporting tools supporting brand, payer, and field teams.

Team Leadership:

Recruit, mentor, and develop a high-performing, US-focused  team, including data scientists and commercial analytics specialists.

Foster a culture of innovation, accountability, and business partnership within the CoE, ensuring continuous skills development and team engagement.

Stakeholder Engagement:

Serve as the lead interface between the CoE and US Commercial business units, including Brand, Market Access, Patient Services, and Customer Engagement.

Translate complex analyses into clear business recommendations and deliver presentations to US commercial leadership, sales teams, and external partners as needed.

Commercial Analytics & Support:

Lead building, implementation, and maintenance of advanced analytics models and dashboards to address critical commercial opportunities (e.g., targeting and segmentation, omnichannel marketing analytics, measurement of return on investment, patient journey analysis, and forecasting).

Drive the use of real-world, claims, and distribution data to improve performance in rare disease launches and mature portfolio management.

Support data-driven decision making by providing market insights, competitive intelligence, and field performance analytics for the US market.

Technology and Innovation:

Evaluate and deploy innovative analytics technologies, AI/ML platforms, and advanced data tools that give US Commercial teams a competitive advantage.

Monitor commercial analytics trends and practices in the US healthcare market and integrate outstanding solutions.

Performance Measurement:

Define and track critical metrics measuring CoE impact within US Commercial performance (e.g., sales growth, market penetration, HCP engagement, launch excellence).

Deliver actionable dashboards, reports, and insights to multiple US Commercial collaborators and regional representatives

You will need to have:
Education:

  • ​Education:
    Master’s or Ph.D. in Data Science, Statistics, Computer Science, Business Analytics, or a related quantitative field.
  • Experience:
    15+ years’ experience in data science, advanced analytics, or commercial analytics roles, including at least 7 years in a senior/leadership capacity with a focus on US Commercial operations in healthcare, biotech, or pharmaceuticals.
  • Technical Skills:
    Deep proficiency in commercial data science and analytics, including statistical modeling, machine learning, segmentation, and forecasting (Python, R, SQL, etc.).
    Hands-on experience with commercial analytics and visualization tools (e.g., Qlik, Power BI, Tableau, Veeva, Databricks).
    Expertise working with US commercial data assets (claims, prescription, distribution, CRM, real-world data, patient support).
  • Leadership Skills:
    Demonstrated ability to build and lead US-focused analytics teams.
    Strong interpersonal, influencing, and communication skills; able to effectively present analytics to commercial executives and field teams.
    Proven record of change management and building commercial analytics capabilities.
  • Analytical Skills:
    Advanced business acumen, with the ability to turn US commercial challenges into actionable analytics projects and insights that fuel growth and performance.
  • Other Requirements:
    Ability to work in a fast-paced, dynamic environment.
    Strong leadership and team management capabilities.
    Experience, working in the pharma or biotech sectors, preferably working within or with the Commercial team
    Knowledge of Syndicated Claims data, Lab data (IQVIA LAAD, Symphony, Specialty Pharmacy/Specialty Distribution).

We would prefer for you to have:

• Proven experience in performing analytics related to US commercial activities for rare or specialty diseases is highly preferred.

Competencies
US Commercial Acumen: Deep understanding of the US pharmaceutical/biotech commercial landscape, including field force dynamics, market access, specialty distribution, and key challenges in rare disease markets.
Visionary Leadership: Ability to set a compelling vision for advanced analytics as a business driver within the US Commercial environment.
Collaboration: Ability to engage and partner across commercial, brand, patient services, and market access teams.
Ethical Judgment: Commitment to ethical data practices, patient privacy, and compliance with US regulatory standards (HIPAA, etc.).

In-Office/Hybrid Statement:

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work on average a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Compensation and other factors:

The annual base pay (or hourly rate of compensation) for this position ranges from $218,000 - $327,000. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

At AstraZeneca's Alexion division for Rare Diseases you will find an environment where work is more than just a job—it's a mission. Our closeness to patients brings us closer to our work and each other. With a rapidly growing portfolio in a nimble biotech atmosphere supported by global resources, tailored development programs are crafted to improve your skills. These programs encourage a deep understanding of our patients' journeys. Here diversity is valued; inclusion is championed; innovation is celebrated; all while making a profound impact on patients' lives. 

Ready to make a difference? Apply now!

Date Posted

05-Feb-2026

Closing Date

14-Feb-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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