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Senior Clinical Data Manager II

Posted date Jul. 28, 2026
Contract type Full time
Job ID R-257186
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Why choose AstraZeneca Spain?

AstraZeneca Spain is a rising force in our global business. With headquarters in Madrid and our global hub in Barcelona, we’ve become an important international centre of excellence in the fight against critical disease. Boasting vibrant universities and business schools, the Barcelona ecosystem is a place where scientists can thrive. We attract a diverse workforce from across the globe, shining a beacon for innovation in a country that’s committed to clinical development.

We invite you to bring your talents to Barcelona where our respiratory medicine R&D and Global Marketing centre offers opportunities in R&D, IT, Commercial and HR. Or join us in Madrid and shape our growth in our BUs (Respiratory, Oncology & CVRM ), and a range of Corporate functions. Additionally, you can find sales roles throughout the country. Together, we’re contributing to a world-leading pipeline of therapeutics and delivering life-changing medicines to patients.

Who do we look for?

Calling all tech innovators, ownership takers, challenge seekers and proactive collaborators. At AstraZeneca Spain, breakthroughs born in the lab become transformative medicine for the world's most complex diseases. Alongside technical expertise, colleagues have the resilience, energy and collaborative mindset to change lanes, work with different teams and start projects from scratch.

Here, diverse minds and bold disruptors can meaningfully impact the future of healthcare using cutting-edge technology. Whether you join us in Madrid or Barcelona, you can make a tangible impact within a global biopharmaceutical company that invests in your future. Join a talented global team that's powering AstraZeneca to better serve patients every day.

Success Profile

Ready to make an impact in your career? If you're passionate, growth-orientated and a true team player, we'll help you succeed. Here are some of the skills and capabilities we look for.

Diverse collaborators

This is a speak-up culture that values collaboration. You’ll proactively bring your unique perspectives, experiences and skills to the table and seek the same from others. With our international team composition and the need for fast-paced collaboration, you’ll always be building new connections with colleagues.

Cutting-edge innovators

When you join us, you’ll be part of a team that embraces digital technology and data to transform the way we work and the work we do. Every day, you’ll help make history, empowered to ignite your creativity and build something enduring.

Resilient trailblazers

Here, the answers aren’t always available. So, you’ll need to bring a fearless, self-starter mindset to navigate uncharted territories. You’ll harness your ceaseless energy to discover and make the necessary connections with colleagues to shape the future and achieve maximum impact.

Agile movers

Seize ownership and excel with autonomy to enjoy the constant rush of ground-breaking discovery. Your ability to anticipate sudden shifts and adapt swiftly will prove critical as you make your mark in an environment that rewards initiative and resilience.

Responsibilities

Job ID R-257186 Date posted 07/28/2026 Job Title: Senior Clinical Data Manager II

Introduction to role:

This role is based in Barcelona, with an on-site commitment of three days a week. Fluency in English is required.

Are you ready to lead study-level data strategy that transforms complex clinical information into decisions that move medicines to patients faster? Do you thrive at the intersection of standards, systems and collaboration, where high-quality data drives confident regulatory submissions and robust science?

In this role, you will coordinate and deliver Clinical Data Management for global clinical studies, partnering closely with external vendors and cross-functional teams. Your leadership will ensure database integrity, consistent application of standards and inspection-ready documentation, accelerating how we learn from trials and shaping the path of our pipeline.

You will join a team that combines scientific curiosity with advanced data and digital approaches to uncover insights and solve difficult problems. Here, your decisions will influence timelines, quality and patient impact across multiple therapy areas, while you continue to learn, stretch and contribute to work that breaks new ground.

Accountabilities:

- Study Data Leadership: Coordinate CDM deliverables for assigned studies, serve as the first-line study contact and plan/deliver according to the operating model and vendor partnership, potentially under mentorship from a Project Data Manager.

- Vendor Oversight: Act as the primary point of contact for the DM vendor; guide the Lead Data Manager/DM Team Lead; track performance against KPIs, timelines and milestones; review budgets and invoices and recommend payment.

- Risk Management: Oversee day-to-day CDM operations; identify and mitigate risks with the DM vendor; escalate issues promptly to maintain study delivery.

- Standards and Data Quality: Apply and drive adherence to corporate, therapeutic/program-specific data capture standards; safeguard database integrity and ensure consistency of data capture for analysis readiness.

- Inspection Readiness and TMF Compliance: Provide input into activities related to regulatory inspections/audits for assigned studies; ensure compliance with Trial Master File requirements relating to the DM vendor.

- Cross-Functional Collaboration: Communicate and collaborate effectively with study team members, statisticians, programmers, clinical and safety colleagues and external partners to anticipate needs and resolve issues.

- Training and Mentorship: Ensure relevant training is completed prior to task execution; mentor junior Clinical Data Management colleagues and take on ad-hoc activities aligned with CDM experience.

- Business Continuity: Maintain continuity of CDM processes and standards for assigned studies, contributing to consistent ways of working across programs.

Essential Skills/Experience:

- University or college degree in the life sciences or related subject, pharmacy, nursing or equivalent relevant degree.

- Knowledge of Clinical Data Management and experience in the Biotech/Pharma/CRO industry.

- Demonstrated current understanding of Good Clinical Data Management Practices (GCDMP) and relevant regulatory requirements.

- Demonstrated experience of clinical databases, different clinical data management systems and electronic data capture (EDC).

- Demonstrate understanding and experience in query management process and reconciliation activities.

- Ability to work flexibly on simultaneous projects and proactively manage time to meet own deadlines.

- Excellent written and verbal communication skills.

- Ability to work in a global team environment.

- Excellent organizational and analytical skills and high attention to detail.

Desirable Skills/Experience:

- Demonstrated knowledge of clinical and pharmaceutical drug development process

- Demonstrated understanding of clinical data system design / development / validation and system interoperability.

- Demonstrated ability to work effectively with external partners

- Understanding of database structures, programming languages, data standards (CDISC) and practices as they apply to CRF design, database development, data handling and reporting

- Knowledge of SQL or SAS software

- Experience leading clinical studies as Data Management Lead

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca: Here you will shape how data and science come together to tackle some of the most complex diseases, working across diverse indications and stages of development. We unite colleagues from different disciplines and partners from academia and industry to spark new ideas and move at pace, supported by modern data, digital and AI capabilities. It is an environment where curiosity is encouraged, learning is continuous and bold decisions are made with kindness and respect—so your expertise can grow while your work meaningfully advances medicines, with opportunities to share impactful results externally when science merits it.

Call to Action: If you are ready to lead the quality and integrity of study data that accelerates life-changing medicines, take your next step with us today!

Date Posted

27-jul-2026

Closing Date

09-ago-2026

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

Reasons to Join

Thomas Mathisen

There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.

Sales Representative Oslo, Norway

There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.

Christine Recchio

Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.

Sales Representative California, United States

Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.

Stephanie Ling

There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.

Sales Representative Petaling Jaya, Malaysia

There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.

What we offer

We're driven by our shared values of serving people, society and the planet. Our people make this possible, which is why we prioritise diversity, inclusivity, balance and sustainability. Discover what a career at AstraZeneca could mean for you.

An award-winning company

We're passionate about being a great place to work, and 84% of our employees would recommend us as an employer. We've been recognised as a Top Employer in Spain, an EFR Family Responsible Business, and we achieved third place in Forbes Spain's Top 50 Best Places to Work list.

Inclusive environment

Diversity and inclusion are embedded in everything we do, and our different views, experiences and strengths enrich our culture. There's no salary gap at AstraZeneca, and the number of female employees has increased by four per cent over the last three years. We've also made all positions fully accessible.

Work-life balance

Your wellbeing means a lot to us, and we're here to support you through all of life's ups and downs. That's why we offer an unpaid leave policy, annual leave, reduced-hours timetables and a host of benefits, including a retirement plan, long service award, and health and travel insurance.

Sustainability initiatives

We're committed to harnessing the power of science to become a more sustainable business. We've reduced our carbon footprint by over 9,000 kg of CO2 over the last two years, and we lead the European GoGreen Project, which aims to introduce environmentally friendly options in our fleet of corporate vehicles.

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