Why choose AstraZeneca Spain?
AstraZeneca Spain is a rising force in our global business. With headquarters in Madrid and our global hub in Barcelona, we’ve become an important international centre of excellence in the fight against critical disease. Boasting vibrant universities and business schools, the Barcelona ecosystem is a place where scientists can thrive. We attract a diverse workforce from across the globe, shining a beacon for innovation in a country that’s committed to clinical development.
We invite you to bring your talents to Barcelona where our respiratory medicine R&D and Global Marketing centre offers opportunities in R&D, IT, Commercial and HR. Or join us in Madrid and shape our growth in our BUs (Respiratory, Oncology & CVRM ), and a range of Corporate functions. Additionally, you can find sales roles throughout the country. Together, we’re contributing to a world-leading pipeline of therapeutics and delivering life-changing medicines to patients.
Who do we look for?
Calling all tech innovators, ownership takers, challenge seekers and proactive collaborators. At AstraZeneca Spain, breakthroughs born in the lab become transformative medicine for the world's most complex diseases. Alongside technical expertise, colleagues have the resilience, energy and collaborative mindset to change lanes, work with different teams and start projects from scratch.
Here, diverse minds and bold disruptors can meaningfully impact the future of healthcare using cutting-edge technology. Whether you join us in Madrid or Barcelona, you can make a tangible impact within a global biopharmaceutical company that invests in your future. Join a talented global team that's powering AstraZeneca to better serve patients every day.
Success Profile
Ready to make an impact in your career? If you're passionate, growth-orientated and a true team player, we'll help you succeed. Here are some of the skills and capabilities we look for.
Diverse collaborators
This is a speak-up culture that values collaboration. You’ll proactively bring your unique perspectives, experiences and skills to the table and seek the same from others. With our international team composition and the need for fast-paced collaboration, you’ll always be building new connections with colleagues.
Cutting-edge innovators
When you join us, you’ll be part of a team that embraces digital technology and data to transform the way we work and the work we do. Every day, you’ll help make history, empowered to ignite your creativity and build something enduring.
Resilient trailblazers
Here, the answers aren’t always available. So, you’ll need to bring a fearless, self-starter mindset to navigate uncharted territories. You’ll harness your ceaseless energy to discover and make the necessary connections with colleagues to shape the future and achieve maximum impact.
Agile movers
Seize ownership and excel with autonomy to enjoy the constant rush of ground-breaking discovery. Your ability to anticipate sudden shifts and adapt swiftly will prove critical as you make your mark in an environment that rewards initiative and resilience.
Responsibilities
Principal Enterprise Architect
Introduction to role:
Are you ready to inspire change and make a significant impact? At AstraZeneca, we are committed to delivering life-changing medicines while embedding sustainability into every aspect of our work. As a Principal Enterprise Architect in Sustainability, you will play a pivotal role in ensuring our architecture decisions align with both business ambitions and IT strategy. This position is focused on strategic planning over a 1-5 year horizon, as well as immediate solution design projects. You will be instrumental in developing architecture standards, technology strategies, and roadmaps that support our mission to tackle the biggest sustainability challenges of our time.
Accountabilities:As a Principal Enterprise Architect, you will:- Provide enterprise design thinking and support across various domains of architecture including Business, Application, Integration, Cloud, Data & Analytics, and AI/ML.- Lead efforts to ensure architecture decisions support business and IT strategy, ensuring compliance with AZ standards, blueprints, and roadmaps.- Participate in architecture assessments and reviews, contributing as a lead reviewing architect or domain expert.- Document and share knowledge and standard methodologies to develop the architecture capability and practice.- Be accountable for developing architecture standards, technology domain strategies, roadmaps, and blueprints.- Define and update 'Transition' and 'To-Be' architectures applying AZ guiding principles.- Support solution development efforts from portfolios, participate in IT initiatives, and provide guidance for better planning and decision-making.- Maintain a view of current and future state architecture within defined focus areas.- Develop architecture building blocks to support enterprise architecture implementation.- Lead or actively participate in enterprise domain teams and working groups.
Essential Skills/Experience:- Relevant technical degree or equivalent- Experience as an enterprise architect authoring and completing architecture roadmaps- Experience producing application strategies/roadmaps for a global enterprise- Experience with rationalisation, consolidation, and integration of technology across business domains- Experience with large justification phase work – product evaluation, case formulation- Experience developing and influencing business strategies with multi-functional team impact- Experience developing and leading innovative solutions- Proven experience of leading change and challenging approaches/ideas- Experience developing and managing relationships with third-party suppliers- Experience designing complex technology solutions aligned to enterprise roadmaps- Experience in designing AI/ML solutions- Strong networking skills with good internal/external links- Strong communication, facilitation, and relationship-building skills- Ability to interpret and communicate technical information into business language- Awareness of marketplace developments and their relevance to AZ- Ability to work well in diverse, multinational teams and influence others positively- Open mind to learning new skills and capabilities- Ability to follow agile and incremental architecture approaches- Strong analytical skills on architecture trade-offs
Desirable Skills/Experience:- Demonstrate initiative, strong customer orientation, and cross-cultural working- People development experience- Budget management experience- Masters or equivalent experience and/or professional certification- Experience in sustainability initiatives in large organizations- Good understanding of industry technology trends regarding Agentic AI- Good eye for business- Understanding of the pharmaceutical/healthcare industry
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace, and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
AstraZeneca offers an environment where technical skills meet emotional intelligence. Join a team of highly qualified professionals who are persuasive communicators with empathy. We focus on the human impact of changes we drive, leading to complete solutions for the business. With the freedom to explore innovative technologies, there's never a dull moment as you create a significant footprint through continuous learning and growth.
Ready to take on this exciting challenge? Apply now to join AstraZeneca's journey towards sustainability and innovation!
Date Posted
05-Jun-2026Closing Date
25-Jun-2026AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
Reasons to Join
Thomas Mathisen
There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.
Christine Recchio
Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.
Stephanie Ling
There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.
What we offer
We're driven by our shared values of serving people, society and the planet. Our people make this possible, which is why we prioritise diversity, inclusivity, balance and sustainability. Discover what a career at AstraZeneca could mean for you.
An award-winning company
We're passionate about being a great place to work, and 84% of our employees would recommend us as an employer. We've been recognised as a Top Employer in Spain, an EFR Family Responsible Business, and we achieved third place in Forbes Spain's Top 50 Best Places to Work list.
Inclusive environment
Diversity and inclusion are embedded in everything we do, and our different views, experiences and strengths enrich our culture. There's no salary gap at AstraZeneca, and the number of female employees has increased by four per cent over the last three years. We've also made all positions fully accessible.
Work-life balance
Your wellbeing means a lot to us, and we're here to support you through all of life's ups and downs. That's why we offer an unpaid leave policy, annual leave, reduced-hours timetables and a host of benefits, including a retirement plan, long service award, and health and travel insurance.
Sustainability initiatives
We're committed to harnessing the power of science to become a more sustainable business. We've reduced our carbon footprint by over 9,000 kg of CO2 over the last two years, and we lead the European GoGreen Project, which aims to introduce environmentally friendly options in our fleet of corporate vehicles.
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