Global Study Manager

Are you ready to drive complex haematology clinical studies from protocol to publication at pace, turning rigorous execution into results that impact patients?  

In this role, you will lead delegated aspects of global study delivery across countries and vendors, ensuring every decision keeps timelines, quality and budget on track.

You will join a highly collaborative team focused on speeding promising science through clinical development. Empowered to take smart risks and move decisively, you will orchestrate internal functions and external partners to remove obstacles and keep the study always inspection-ready. Can you see yourself uniting data, operations and suppliers to accelerate decisive progress for people with blood cancers?

Accountabilities:

• Study Documentation Leadership: Contribute to the development of study documents and amendments, ensuring template and version compliance.

• Lead the preparation of delegated study documents such as the Informed Consent Form, master Clinical Study Agreement and country-specific materials, as well as external service provider documents including specifications and study procedures.

• Vendor and CRO Oversight: Manage the set-up of third-party vendors, assess statements of work and budgets, and run the change order process. For outsourced studies, support the Global Study Director/Associate Director in partnering with the CRO Project Manager to deliver to agreed timelines, budget and quality, maintaining and documenting appropriate oversight.

• Cross-Functional Delivery: Partner closely with enablement teams and clinical experts across Data Management, Procurement, Regulatory, Patient Safety and Quality Assurance, and align seamlessly with CROs and other providers to ensure efficient delivery to time, cost and quality objectives.

• Study Start-Up, Maintenance and Close-Out: Plan and conduct internal and external meetings, including investigator and monitor meetings. Ensure the supply of investigational product and study materials by liaising with Global Clinical Supply and external providers.

• Risk and Quality Management: Support risk management and quality efforts to ensure compliance with ICH GCP, AstraZeneca SOPs, policies and guidelines, keeping the study inspection-ready at all times. Ensure all documents within scope are complete and verified for quality in the Trial Master File.

• Budget and Contracts Stewardship: Support the Global Study Director/Associate Director with budget management and external service provider invoice reconciliation, and provide clear requirements to inform selection and oversight of external contracts.

• Inspection Readiness and Audit Support: Support the study team in audits and regulatory inspections, ensuring processes and documentation meet global clinical standards and Quality & Compliance requirements.

• Continuous Improvement and Non-Drug Projects: Contribute to the review of new or amended SOPs and guidance documents throughout the study lifecycle. Lead or participate in process improvement initiatives and non-drug project work as agreed with your manager, scaling local learnings to global impact.

• Progress and Impact: From day one, you will secure robust start-up and vendor alignment; in the first months you will establish rhythm across functions and countries; over time, your oversight will reduce cycle times, enhance quality, and help deliver conclusive data that advances our haematology pipeline.

Essential Skills/Experience:

• University level bachelor’s degree (or equivalent), preferably in medical or biological sciences or discipline associated with clinical research.

• Minimum of 5 years progressive experience in clinical research, with at least 3 years of clinical development project management experience, or equivalent.

• Extensive knowledge of clinical research regulatory requirements (incl ICH-GCP) and demonstrated abilities in clinical study management processes and clinical/drug development.

• It is essential to have at least 1 year of experience as a Global Study Manager.

• Extensive and proven experience in driving operational delivery to timelines, costs, and quality.

• Proven experience leading delivery through internal and external organizations.

• Strong, demonstrated abilities/skills in matrix team leadership.

• Strong abilities in establishing and maintaining effective working relationships with internal and external co-workers and stakeholders, along with strong conflict management skills.

• Experience in providing clear requirements and selection of external contracts. • Excellent communication and interpersonal skills.• Strong strategic and critical thinking abilities.• Strong organizational and problem-solving skills.

• It is a plus to have experience in Hematology or Oncology areas.

Desirable Skills/Experience:• Higher university degree e.g., PhD, MSc.

• Experience in all phases of a clinical study lifecycle.

• Basic knowledge of GXP outside of GCP (i.e., GMP/GLP).

• Experience in haematology therapeutic area.

• Vendor management experience (e.g., IRT, labs etc.).

Why AstraZeneca: Here, ambition meets action. You will work in an environment where bold decisions are encouraged, unexpected teams gather in the same room to unleash fresh thinking, and science and technology come together to tackle some of the toughest challenges in cancer. When opportunity emerges, we mobilise in weeks, not months—aligning protocol, data and publication at pace—so patients can benefit sooner. You will be trusted to lead, supported by colleagues who value kindness alongside ambition, and given the platform to turn operational excellence into real patient impact.

Call to Action: If you are ready to lead global haematology studies with speed, precision and purpose, step forward and help us deliver the next wave of evidence that changes patients’ lives!

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.