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Associate Principal Physician Scientist, Genomics

Posted date Sep. 25, 2024
Contract type Full time
Job ID R-209637
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Why choose AstraZeneca Spain?

AstraZeneca Spain is a rising force in our global business. With headquarters in Madrid and our global hub in Barcelona, we’ve become an important international centre of excellence in the fight against critical disease. Boasting vibrant universities and business schools, the Barcelona ecosystem is a place where scientists can thrive. We attract a diverse workforce from across the globe, shining a beacon for innovation in a country that’s committed to clinical development.

We invite you to bring your talents to Barcelona where our respiratory medicine R&D and Global Marketing centre offers opportunities in R&D, IT, Commercial and HR. Or join us in Madrid and shape our growth in our BUs (Respiratory, Oncology & CVRM ), and a range of Corporate functions. Additionally, you can find sales roles throughout the country. Together, we’re contributing to a world-leading pipeline of therapeutics and delivering life-changing medicines to patients.

Who do we look for?

Calling all tech innovators, ownership takers, challenge seekers and proactive collaborators. At AstraZeneca Spain, breakthroughs born in the lab become transformative medicine for the world's most complex diseases. Alongside technical expertise, colleagues have the resilience, energy and collaborative mindset to change lanes, work with different teams and start projects from scratch.

Here, diverse minds and bold disruptors can meaningfully impact the future of healthcare using cutting-edge technology. Whether you join us in Madrid or Barcelona, you can make a tangible impact within a global biopharmaceutical company that invests in your future. Join a talented global team that's powering AstraZeneca to better serve patients every day.

Success Profile

Ready to make an impact in your career? If you're passionate, growth-orientated and a true team player, we'll help you succeed. Here are some of the skills and capabilities we look for.

Diverse collaborators

This is a speak-up culture that values collaboration. You’ll proactively bring your unique perspectives, experiences and skills to the table and seek the same from others. With our international team composition and the need for fast-paced collaboration, you’ll always be building new connections with colleagues.

Cutting-edge innovators

When you join us, you’ll be part of a team that embraces digital technology and data to transform the way we work and the work we do. Every day, you’ll help make history, empowered to ignite your creativity and build something enduring.

Resilient trailblazers

Here, the answers aren’t always available. So, you’ll need to bring a fearless, self-starter mindset to navigate uncharted territories. You’ll harness your ceaseless energy to discover and make the necessary connections with colleagues to shape the future and achieve maximum impact.

Agile movers

Seize ownership and excel with autonomy to enjoy the constant rush of ground-breaking discovery. Your ability to anticipate sudden shifts and adapt swiftly will prove critical as you make your mark in an environment that rewards initiative and resilience.

Responsibilities

Job ID R-209637 Date posted 09/25/2024

Location: Barcelona, Spain (On-site): We require 3 days working from the office and 2 days working from home.

Are you ready to make a more meaningful impact on patients' lives around the globe? Here at AstraZeneca, we offer the opportunity to make a significant difference. Our science-driven approach allows us to transform lab-born breakthroughs into transformative medicines for the world's most complex diseases. With our ground-breaking pipeline, the future is bright. There's no better time to join our global, growing enterprise as we lead the way for healthcare and society.

What You’ll do

AstraZeneca's Centre for Genomics Research (CGR) is currently seeking a physician with a research background to join our dedicated team focused on the company-wide Genomics Initiative which includes the analysis of up to 2 million genomes. In this role, you will apply your medical knowledge to help interpret DNA and multi-omics research data from AstraZeneca's clinical trials and broad biobanks representing ancestry diverse populations. Furthermore, you will play a pivotal role in leading deep-phenotyping and cohort stratification efforts aimed to further improve opportunities of identifying and validating new therapeutic targets for drug development. You will also contribute to the harmonization of healthcare records collected from a diverse range of geographical regions, an essential activity for maintaining data consistency and reliability in our research efforts.

The successful candidate will work with leaders in human genomics delivering innovative science to genome analytics. You will also work closely with experts in translational science, drug discovery, pre-clinical modelling, and clinical development; thus, contributing to the broader objectives and success of the company-wide Genomics Initiative. This unique role requires an individual who is innovative, passionate about science, and can generate and lead original projects in a global R&D environment. The role will be primarily office-based, with some national and/or international travel to support projects, participate in team development meetings and attend conferences.

What you will be doing on daily basis? You will be…

  • Coordinating analyses within AstraZeneca’s Centre for Genomics Research
  • Applying innovative quantitative genomic analyses to large-scale cohort studies to identify clinically relevant disease and response loci
  • Deliver novel insights into the biology of disease, validation of new targets for medicines and the improvement of selection of patients for clinical trials
  • Providing detailed reports regarding the study design, analysis approach and research findings and presenting to study teams
  • Champion and lead the strategic direction of own projects and initiatives.
  • Seek and apply best practices in processes, data analysis, and decision-making in leading project teams in a virtual environment
  • Contribute to the overall success of the wider AstraZeneca BioPharmaceuticals R&D functions.
  • Ensuring own work, and work of team, is compliant with Good Laboratory Practice, Safety, Health and Environment standards and all other internal AstraZeneca standards and external regulations

Qualifications, Skills and Experience Required:

Essential:

  • Degree in Medicine
  • PhD degree (or equivalent experience)
  • Experience in large-scale data analysis
  • Ability to communicate effectively with team members and non-experts, both verbally and through documentation
  • High level understanding or interest in the potential of genomics to impact drug discovery
  • In-depth understanding of medicine in its broadest context
  • Desire and willingness to ‘Follow the Science’ beyond core disease area of expertise
  • Ability to carry out duties under minimal supervision
  • Excellent interpersonal skills and willingness to work within a team in a quickly evolving environment
  • Track record of peer-reviewed publications in high-level scientific journals

Desirable:

  • Previous experience in a similar role
  • Experience harmonising clinical phenotype information and diverse health datasets  
  • Pragmatic experience with data querying and data exploration tools
  • Experience in case-control sequencing based statistical analyses
  • Experience quantifying and interpreting the clinical relevance of rare variants
  • Familiarity working on genomics studies involving one of AstraZeneca’s core therapeutic areas (see: https://www.astrazeneca.com/our-therapy-areas.html)
  • Clinical experience, now seeking entry to the biotech/pharmaceutical industry

Why AstraZeneca?

Make a more meaningful impact to patients’ lives around the globe

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

Ready to embrace new and varied opportunities to develop and learn? Join us at AstraZeneca's Biopharmaceuticals R&D division! Apply now and be part of our mission to improve patient access to healthcare globally.

Where can I find out more?

Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

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Reasons to Join

Thomas Mathisen

There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.

Sales Representative Oslo, Norway

There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.

Christine Recchio

Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.

Sales Representative California, United States

Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.

Stephanie Ling

There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.

Sales Representative Petaling Jaya, Malaysia

There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.

What we offer

We're driven by our shared values of serving people, society and the planet. Our people make this possible, which is why we prioritise diversity, inclusivity, balance and sustainability. Discover what a career at AstraZeneca could mean for you.

An award-winning company

We're passionate about being a great place to work, and 84% of our employees would recommend us as an employer. We've been recognised as a Top Employer in Spain, an EFR Family Responsible Business, and we achieved third place in Forbes Spain's Top 50 Best Places to Work list.

Inclusive environment

Diversity and inclusion are embedded in everything we do, and our different views, experiences and strengths enrich our culture. There's no salary gap at AstraZeneca, and the number of female employees has increased by four per cent over the last three years. We've also made all positions fully accessible.

Work-life balance

Your wellbeing means a lot to us, and we're here to support you through all of life's ups and downs. That's why we offer an unpaid leave policy, annual leave, reduced-hours timetables and a host of benefits, including a retirement plan, long service award, and health and travel insurance.

Sustainability initiatives

We're committed to harnessing the power of science to become a more sustainable business. We've reduced our carbon footprint by over 9,000 kg of CO2 over the last two years, and we lead the European GoGreen Project, which aims to introduce environmentally friendly options in our fleet of corporate vehicles.

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Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.