Bio-Process Technician (24/7 Shift)

Bio-Process Technician (24/7 Shift)

Location: Monksland, Athlone

Competitive salary and benefits

Opening date: 06/02/2026

Closing date: midnight 22/02/2026

Shift working required, including weekend working and periodic rotation between day and night shifts; shift pattern may vary according to business requirements

Are you ready to apply your bioprocess expertise to deliver life-changing therapies for people living with rare diseases? Join a manufacturing team where precision, ownership, and cross-functional collaboration turn complex science into reliable supply for patients who count on us.

In this shift-based role, you will become fully trained and competent across core operations and develop a specialist focus where you lead improvements for your area. Do you thrive in a fast-moving environment where you mentor others, resolve deviations, and elevate standards in cGMP every day? Your impact will be felt on the floor and, ultimately, by patients whose journeys drive our mission.

Accountabilities

• Core Production Operations: Independently perform cell culture, media preparation, purification, buffer preparation, and equipment preparation to deliver consistent, compliant batches.
• cGMP Execution and Documentation: Complete all tasks according to SOPs and batch records with full attention to detail and excellent documentation, safeguarding product quality and patient safety.
• Area Specialism and Technical Leadership: Develop subject matter expertise in at least one operational area and act as a Champion, leading improvements and excellence within the shift team.
• Deviation and Change Control: Assist with investigations of operational deviations through the QTS system; lead and own investigations and change controls when required to restore control and prevent recurrence.
• Training and Knowledge Transfer: Mentor colleagues in SOPs, process execution, and equipment operation; act as designee to prepare and deliver shift handovers, reporting to leadership, technical services, and engineering partners.
• Partner Engagement: Engage with Technical Services, QA, and Automation to resolve issues; interface effectively with MCS to anticipate, diagnose, and troubleshoot operational challenges.
• Validation and Start-up Support: Assist in facility and equipment start-up and validation; provide input on installation, start-up, operation, and troubleshooting to support new product introduction into sustaining operations.
• Lean and Continuous Improvement: Demonstrate a Lean attitude and lead by example, driving standard work, waste reduction, and process stability.
• EHS, GMP, and Productivity: Be a positive example in environmental health and safety, GMP compliance, and productivity to support a high-performance culture.
• Shift Operations: Work a varied shift pattern that typically includes weekends and periodic rotation between day and night, aligning with business requirements.

Essential Skills/Experience

• Trained and competent to independently perform core production tasks in cell culture, media preparation, purification, buffer preparation, and equipment preparation.
• Responsible for execution of all tasks according to SOPs and batch records in a cGMP environment, ensuring full attention to detail and excellent documentation skills.
• High level of SME knowledge and experience in at least one area of operations (e.g., Level 1/Level 2); effective process leader within that area.
• Able to anticipate and troubleshoot operational issues and interface effectively with MCS.
• Engage with partners including Technical Services, QA, and Automation to resolve issues.
• Willing to seek the schedule, identify priorities, and organise work teams locally.
• Be a mentor and a trusted source of knowledge, able to effectively impart information and knowledge to others.
• Be a positive example to others in all areas of EHS, GMP, and productivity.
• Able to act as designee if required to prepare and deliver shift handovers, reporting out to Biologics LT/TS/Eng.
• Lead and own investigations and change controls if required; assist with the investigation of operations deviations through the QTS system.
• Demonstrate a Lean perspective and lead by example in this area.
• Shift working required, including weekend working and periodic rotation between day and night shifts; shift pattern may vary according to business requirements.

Desirable Skills/Experience

• Cross-trained across multiple unit operations, with flexibility to move between cell culture and downstream purification as needed.
• Experience with electronic systems supporting manufacturing (e.g., QTS, MCS) and familiarity with data-driven troubleshooting.
• Exposure to equipment installation, qualification, and validation, including start-up of new lines or technologies.
• Proven contributions to SOP and batch record creation or optimization.
• Formal training in root cause analysis, problem-solving, or Lean/continuous improvement methodologies.
• Strong communication skills to engage confidently with QA, Technical Services, Automation, and operations leadership during investigations and handovers.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why this essential worker role works fully onsite. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca's Alexion division, we embrace an opportunity where work transcends the ordinary. Our closeness to patients brings us closer to our work and each other. With a pioneering spirit, we are unique in R&D and healthcare. Here, diversity is valued, inclusion is championed, and life-changing ideas can come from anywhere. We celebrate each other's successes while maintaining kindness as a core value. Join us to make a profound impact on patients' lives while growing your career in a supportive environment.

Ready to make a difference? Apply now to join our team!

Date Posted

06-Feb-2026

Closing Date

22-Feb-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.