Skip to main content
Search roles

Technician, Filling - Operations (2nd & 3rd Shift)

Posted date 09/17/2021
Contract type Full_time
Job ID R-119634
Apply now

What you'll do

As a member of our Operations team, you’ll be on the front line, directly impacting patients by making sure we manufacture our products effectively, quickly and collaboratively. Every day, you’ll experience fresh challenges as you navigate the ever-changing landscape of Operations – which means you’ll have plenty of opportunities for personal and professional development. Backed by a supportive team, be part of accelerating our operational excellence with innovations in cutting-edge science, Lean ways of working and fast changing digital technologies.

In our fast-paced, growing environment, embrace an exciting opportunity to build a long-term, varied career. Experience leading edge digital innovations such as artificial intelligence and augmented reality that drives efficiencies and keeps a balanced workload. Enjoy varying shifts in a regulated but stimulating atmosphere. And gain invaluable experience and exposure in a team that wants to see you succeed.

Why Global Operations at AstraZeneca?

From molecule to medicine, our pipeline to deliver to patients is ever-growing and increasingly complex. Our Operations Team brings the Research & Development pipeline to life, from development and manufacturing, through to testing and delivery. We have the ambition to make our processes quicker, more affordable and more sustainable, leading to better outcomes.

It makes us proud to know we’re working with medicines that address unmet needs. With every decision we make, we are conscious of our very clear responsibility to deliver. So, we create a culture of continuous improvement – driven by our people.

With teams across 25 locations and a reach into global communities, your ideas can become a reality at scale, with the potential to genuinely improve the lives of patients and their families. Join the team where everyone feels a personal connection to the people that we impact.

Success Profile

Our success profile gives you a better idea of whether the job is right for you. These are the behaviours you’ll need in order to thrive.

Problem solver

Disciplined thinkers and doers, we thrive in our often intense and varied environment, seeking out new challenges and working towards new solutions. As an avid problem solver, you’ll do well here.

Eager to learn

If you’re proactive with a thirst for knowledge, we’ll provide you with every resource to grow. We’ll give you what you need to achieve autonomy, advance your career and work with advanced technologies.

Open to change

In a global biopharmaceutical, things change quickly – and it’s up to us in Operations to make sure that change goes smoothly. The ability to be adaptable plays a huge role in whether our continuous improvement succeeds.

Patient-first mindset

The medicines you manufacture, package and deliver in Operations help people. If you have the passion and the drive to make people’s lives better – then this is the place for you.


Job ID R-119634 Date posted 09/17/2021

At AstraZeneca, we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.

Our West Chester Supply Site is a very dynamic and growing manufacturing site within the AstraZeneca Global Operations network and is located just north of Cincinnati, Ohio.  In addition to serving as the global COVID vaccine production site for AstraZeneca, the West Chester site encompasses Bulk API Microsphere manufacturing, Aseptic Pharmaceutical Formulation, multi-line Isolator/Barrier Vial and Syringe Filling, and specialty Packaging Operations for Vials and Auto-Injectors that supports growing franchises in Diabetes, Respiratory, and Vaccines.  Our site is one of 30 production facilities in 18 countries with over 700 people collaborating to connect powerful medications to patients in more than 60 countries around the world.    We focus on providing a collaborative environment where everyone feels comfortable and able to be themselves.  Being able to bring your full self to work every day is at the core of AstraZeneca’s priorities. On-site amenities include a Health and Wellness clinic, as well as a Cafeteria Grille serving breakfast and lunch items for employees and guests. We also have a Great Place to Work Counsel, involving committees of employees who coordinate several activities related to community outreach, sustainability, health and wellness and social events.

The Technician, Filling is a direct labor position reporting to a Process Execution Team Process Facilitator on the Manufacturing floor, which supports Filling operations. This position will require working in various Controlled/Non-Classified areas. The Technician operates equipment, performs in-process monitoring, line clearances, OEE data collection, cosmetic inspection and completes batch record entries in accordance with cGMPs.

Two shifts are available:

  • 2nd Shift- 2pm-10:30pm
  • 3rd Shift- 10pm-6:30am

What you’ll do:

  • Perform cleaning and housekeeping activities for assigned areas as required to maintain a cGMP environment.
  • Perform batch record and GMP documentation entries. Maintain records and/or logs as required in performance of job responsibilities. This will include mathematical computation.
  • Knowledge of product security controls including controlled substance handling and outgoing quality.
  • Be able to start up and make minor adjustments to machinery.
  • Computer on-line may require some data input. This includes SCADA and HMI entries.
  • Perform the duties of operating assigned machinery consisting of servicing machines with materials, removing finished materials from machine tables, and assuring smooth flow of product.
  • Perform visual and physical checks of in-process and finished materials as requested.
  • Knowledge of light material or equipment (non-motorized lifts).
  • Perform inventory control and reconciliation activities, which may require use of SAP.

Essential for the role:

  • High school diploma or GED required.
  • Must have the ability to effectively understand, read, write, communicate and follow instructions in the English language.
  • Good attention to detail is required.
  • Individual must be capable of keeping accurate records and performing mathematical calculations.

Desired for the role:

  • Prior production experience and experience working in a LEAN manufacturing environment.
  • 0-1 year of experience in a pharmaceutical or GMP regulated environment.
  • Knowledge of cGMPs and FDA policies/procedures.

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial -finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

Reasons to Join



We offer training as soon as you join. This will leave you feeling confident about the job ahead and excited to get started. From there, you have the opportunity to complete qualifications, develop into a leader within your area of expertise and inspire others to reach their potential.

Future-focused technology

With automation and machine learning changing the Operations environment, we are investing in cutting-edge technologies that improve flow whilst making you more effective in your work. And our Lean ways of working will help you innovate with a digital-first mindset.

Work/life balance

Whether you’re working around studies, parenthood or caring for loved ones, our shift patterns help make work manageable and life a lot easier. It’s all part of our commitment to making Operations the place for agile and committed innovators.


In Operations, you can move both upwards and sideways. Whether you want to aim for management, use your skills in a different department or even help other sites achieve consistency, we want our people to grow in the direction that is right for them.

We’ll keep you up to date

Sign up to be the first to receive job updates.

Interested InSearch for a category and select one from the list of suggestions. Search for a location and select one from the list of suggestions. Finally, click “Add” to create your job alert.

Glassdoor logo Rated four stars on Glassdoor

Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.