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Senior Scientist

Location Waltham, Massachusetts, United States Job ID R-081669 Date posted 06/02/2020

AstraZeneca Pharmaceuticals LP

Role: Senior Scientist

Full-Time; Mon-Fri (40 hours/week)

Develop and perform vitro and ex vivo immunological assays including T cell activation assays, dendritic cell assays and

tumor immune co-culture assays. Perform and establish assays to determine functional effects of target activation and

inhibition by using a variety of immune endpoints. Study tumor intrinsic mechanisms that regulate immune cell function and

build internal capabilities that contribute to the overall success of small molecule drug discovery programs. Design and

execute vivo PD read outs and perform multicolor flow cytometry to immunophentype lymphoid and myeloid populations in

tumor microenvironments. Process healthy and cancer patients’ blood to perform immune cell isolations using magnetic,

isolation and FACS. Perform various protein detection techniques such as western blotting, MSD multiplex cytokine

analysis, Luminex and ELISA.

REQUIREMENTS:         Bachelor’s degree or a foreign equivalent in Pharmaceutical Science or a related field, plus four (4) years of experience in the job offered, or as a Scientist, Research Scientist, Research Associate or a related position. Must have four (4) years of experience with: molecular and protein assays; mammalian cell culture; western blotting; quantitative RT-PCR; protein detection assays; human and mouse cellular assays; and multi-color flow cytometry.

OTHER:                           Location: Waltham, MA (AstraZeneca Pharmaceuticals LP);

                                           If offered employment, must have legal right to work in U.S.

Click Apply to submit application.  No calls please.  EOE.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.