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Associate Scientist II / Scientist I - Molecular Biology

Location San Francisco, California, United States South San Francisco, California, United States Job ID R-061143 Date posted 09/12/2019

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.

Position Summary:
As an Associate Scientist II or Scientist I in Clinical Pharmacology Biologics and Bioanalysis you will provide support for biotherapeutic projects, including but not limited to the development, validation, and conduct of molecular biology-based assays and/or immunoassays for the determination of drug exposure or relevant biomarkers in biological matrices.

Main Responsibilities

  • Execute assay development, qualification and validation and sample testing in a timely manner
  • Develop molecular biology-based assays and immunoassays for measurement of drug exposure and potential pharmacodynamic markers in biological matrices
  • Conduct bio-analytical sample analysis in support of Non-GLP pharmacology studies and clinical trials
  • Prepare Standard Operating Procedures, validation protocols and reports and contribute to technical reports
  • Maintain lab routines to ensure lab safety and instrument compliance


For Associate Scientist II

  • Ph.D. degree in biological science or related field
  • 0-1 years' academic or industry experience

For Scientist I

  • Ph.D. degree in biological science or related field
  • 2+ years post-doc or industry experience

Skills Required:

  • Strong background in molecular biology and assay development, including experience with qPCR, ELISA, MSD, and other platforms
  • Experience working with anti-sense oligos or siRNA in biological matrices such as whole blood, serum, and plasma
  • Experience with experimental design and data interpretation.
  • Proficiency with spreadsheet, word processing, and graphical computer programs (MS EXCEL, MS WORD, Graphpad Prism, for example)
  • Knowledge of assay validation guidelines and GLP regulations
  • Teamwork in a matrix environment
  • Ability to multi-task

Next Steps - Apply!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.