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【Medical】Science Lead (Autoimmune), Medical, RIA

Location Kita-ku, Ōsaka, Japan Tokyo, Tokyo, Japan Job ID R-079014 Date posted 07/03/2020


Execute Evidence generation strategy in responsible therapeutic area under Medical Affairs Director oversight by closely collaborating with MA members, External experts, EOR (Evidence and Observational Research) team and global counterparts so that the studies are properly planned, delivered and published to address Key Research Questions and unmet medical needs that support Business strategy.

Deliver high-quality scientific and strategic evidence through AZSS and ESR, with Scientific publications by closely collaborating with internal and external stakeholders.

Support or Supervise medical key messages, Materials for KEE communication, MSL training plans/materials/implementation, and incorporation of MSL insights into Evidence plan in collaboration with MAM/MAD/MSLM/MSLD.


Medical Brand Stratagy


  • Develop and update evidence generation part assigned by MAD
  • Ensure quality of information in responsible evidence plan

Evidence Generation

Data generation strategy

  • Execute Data generation strategy under MAD oversight by closely collaborating with EOR team.
  • Provide presentation and lead discussion in ABM/CIM for evidence generation strategy creation.

ESR plan to execution

  • Review ESR proposals, protocols and publications and provide scientific feedbacks (incl. investigator relations)

  • Ensure validity of proposal, protocol and impact on medical practice at LREG and GREG.

✓AZSS plan to execution

  • Create study design concept(SDC) and represent the responsible TA in the AZSS study team by providing medical/scientific inputs and leading discussions.
  • Manage progress and budget of each AZSS.

Scientific Publication

  • Prepare abstracts, manuscripts and presentations and review publications by collaborating with internal/external authors & presenters to execute publication strategy/plans.


Internal training plan to execution

  • Collaborate with MAM/MAD/MSLM/MSLD to develop internal training plans and materials.

Material Creation

  • Collaborate with MAM/MAD/MSLM/MSLD to develop Medical Key Messages and TA materials




Knowledge on clinical medicine

  • Recognized as a clinical medicine expert in the therapeutic area, and is knowledgeable enough to give advice to others

✓Scientific knowledge on AZ and related products

  • Knowledgeable about AZ and related products in the therapeutic area, enough to be regarded as an expert by KEE in the therapeutic area

Statistical knowledge

  • Understand the statistical aspect of articles and company/investigator sponsored studies, and is knowledgeable enough to explain to customers and internal stakeholders

Therapeutic area knowledge

✓Knowledge on patients

  • Have knowledge on the current status and prospect of Patient(s) Journey and treatment reality in the therapeutic area that is comparable to that of clinicians in the therapeutic area

Knowledge on KEE (for selection)

  • Have highly accurate information on KEE/Next generation and surrounding environment at global/national level in the therapeutic area, to the extent that one can give advice to other functions

Knowledge on AZ, AZ products, competitors, competing products, and patient population

  • Understand the size/characteristics of patient population in the therapeutic area, and have knowledge to the extent that one can figure out when to take actions as Medical, based on  competitors’ brand strategies, scientific strategies (Medical aspect of the strategies), and regulatory landscape

Clinical study

Proven ability of clinical study planning/execution

  • Knowledgeable enough to develop difficult NIS plan, review ESR’s SDC/protocol, and manage the progress

*Example of a “difficult” study: Clinical study on a disease with no guidance/indicator


Knowledge and proven ability of publication work

  • Familiar with publication related work and knowledgeable enough to explain to others. Systematically organize/accumulate knowledge on publication related media and their characteristics learned from experience, and share the information with others


Knowledge on compliance

  • Correctly understand overall compliance rules in the industry, and knowledgeable enough to make appropriate business decisions and reflect them into action

【Basic Skills】


Communication skills

  • By eliciting views and opinions from the other party and understanding agreement/disagreement with AZ/own opinions, derive a reasonable agreement or conclusion, and have the other party to take expected actions


Logical thinking

  • Have logical thinking to deal with a complicated, or seemingly insoluble incidence, based on the big picture of the incidence

Information collection

Information collection skills

  • Define necessary information, and collect necessary information efficiently


  • Speaking skills: Be able to effectively negotiate at work
  • Reading/writing skills: Correctly comprehend English sentences in a natural speed, and create sentences smoothly


  • Project management skills: Manage projects and work on one’s own by assuming variable possibilities and risks

Education, Qualifications, and Experience

<Essential ​>

  • Ph.D. in Medical/Life science/Related area or Qualified Medical Doctor
  • Excellent knowledge of science, disease area and clinical research
  • Capable of conducting discussions with top-tier experts
  • Interest in a long-term career in the pharmaceutical industry
  • Biz level in English/Japanese – speaking ability at level to participate in global working groups
  • An ability to travel

  • Qualified Medical Doctor
  • Experience in Clinical Medicine
  • Experience of basic or clinical research handling
  • Advanced English capability
  • Understanding of multiple aspects within Medical Affairs
  • Experience of Medical Affairs function within a pharmaceutical industry .

勤務地/Location:Osaka or Tokyo 


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.