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Director, Precision Medicine Lead - Oncology

Location Mississauga, Ontario, Canada Job ID R-157517 Date posted 23/01/2023

At AstraZeneca, we pride ourselves on crafting a collaborative culture that champions knowledge-sharing, ambitious thinking and innovation – ultimately providing employees with the opportunity to work across teams, functions and even the globe.

Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to create a strong culture of collaboration and teamwork by engaging face-to-face in our offices 3 days a week. Our head offices are purposely designed with collaboration in mind, providing space where teams can come together to strategize, brainstorm and connect on key projects.

Our dedication to sustainability is also central to our culture and part of what makes AstraZeneca a great place to work. We know the health of people, the planet and our business are interconnected which is why we’re taking ambitious action to tackle some of the biggest challenges of our time, from climate change to access to healthcare and disease prevention.

Are you excited about Precision Medicine? Would you like have an impact on patients’ lives and contribute to eliminate cancer as a cause of death? If so then join us!

We’re investing like never before in our people, in growth, and in new diagnostic techniques and technologies. There are opportunities at every turn, with a variety and breadth that is uncommon to find and an industry-leading pipeline in oncology. Scientists at AstraZeneca are working every day to turn science fiction into science fact. Our ambition - to develop innovative, targeted medicines for every patient that needs them - and to match those treatments to patients most likely to benefit from them – is now a reality. This approach, known as Precision Medicine, is based on those individual characteristics that make some patients respond to treatment better than others. We use this knowledge to develop diagnostic tests that doctors can use to help prescribe the best treatment for each patient. Indeed, it’s now become common practice for patients with cancer to be offered such diagnostic tests before their treatment plan is agreed.

The AstraZeneca Companion Diagnostics Unit within the Precision Medicine and Biosamples function drives scientific leadership through the delivery of innovative companion diagnostics enabling our oncology ambition to transform the lives of patients living with cancer, and ultimately eliminate cancer as a cause of death. 

We do this by:

  • Leading the development of diagnostics across AstraZeneca’s early and late stage oncology portfolios through close collaborations with our external diagnostic partners.

  • Leading the development and implementation of patient selection strategies to deliver companion diagnostics programs in support of our business priorities.

  • Leading companion diagnostic regulatory interactions to secure companion diagnostic  approvals in major markets

  • Collaborate across AstraZeneca with colleagues in multiple Clinical functions plus commercial to help drive market uptake.

  • Developing strategies for early cancer detection, near patient testing and implementing testing options for minimal residual disease and early treatment interventions. 

  • Utilising artificial intelligence diagnostic solutions and seeing software as a medical device.

  • Developing specific disease area strategies (e.g. lung cancer, breast cancer or hematological malignancies) and new diagnostic modalities.

  • Collaborating closely with fellow pharma companies on joint assets.

Join this fantastic, collaborative team and be part of our success; we have already delivered over 50 innovative/impactful companion/complementary oncology diagnostic approvals across the major markets of the US, EU, Japan and China since 2014 and we need you to help us take the next steps in patient-centric diagnostic development.

Typical Accountabilities of the Director, Precision Medicine Lead - Oncology, what you will be doing:

As a Director, you’ll be a member of the Oncology Companion Diagnostic Unit (CDU).  Your objective will be to ensure that innovative companion diagnostic tests or equivalent segmentation tools are delivered to our oncology drug projects. Drawing on world-class expertise and personal experience in companion diagnostic development you will ensure the adoption of Precision Medicine approaches within the AstraZeneca business.  You will also provide leadership and support to a pool of fellow diagnostic experts to ensure delivery of a diagnostic strategy.

Your role will also involve contributing to the personal development of project team members. Providing expert advice on strategic and innovative Precision Medicine approaches and companion diagnostic developments to development teams, you’ll be instrumental in ensuring that we adopt world-class practice in the field.

Education, Qualifications, Skills and Experience:

Essential (Minimum):

  • PhD or equivalent experience in a relevant subject.

  • Experience of companion diagnostic tests or patient biomarker/segmentation tools in clinical development.

  • Experience of Precision Medicine approaches and diagnostic development within the relevant therapeutic area.

  • Effective communication, stakeholder, influencing skills and programme management.

  • Significant understanding of the functions involved in companion diagnostic development and how they contribute to achieving successful diagnostic submissions and approvals

Desirable:

  • Significant previous experience in a similar role in different companies.

  • Delivery of companion diagnostics, regulatory interactions and commercialisation.

  • High quality scientific expertise in the field of Precision Medicine or relevant therapeutic area as evidenced by publications.

Great People want to Work with us! Find out why:

·GTAA Top Employer Award for 8 years:https://reviews.canadastop100.com/top-employer-astrazeneca-canada

·Best Workplace Culture Award at the 2018 Canadian HR Awards:https://www.linkedin.com/pulse/thriving-best-workplace-culture-gena-restivo/

·Learn more about our culture:https://www.linkedin.com/posts/genarestivo_greatpeople-greatplacetowork-topemployers2020-activity-6608742174811049985-N-8G

·Browse AstraZeneca's Oncology YouTube channel to find out more about our focus:https://www.youtube.com/playlist?list=PLgfkdJlwmkT7Sj9A_N6J_9OKcnBW5eNyy

Are you interested in working at AZ, apply today!

AstraZeneca is committed to taking every reasonable precaution to protect employees, our customers and the healthcare systems in the communities in which we serve. In an effort to protect the wellbeing of our employees and customers, full COVID-19 vaccination is an essential requirement of all positions at AstraZeneca. As such, all offers of employment will be conditional upon either (i) proof of full COVID-19 vaccination or (ii) proof of need for accommodation under relevant human rights legislation, and AstraZeneca’s determination that the requested accommodation can be provided without undue hardship.  You will be required to submit proof of full vaccination or proof of need for accommodation during our background screening process.

AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailingAZCHumanResources@astrazeneca.com.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

50056698 F PRSP

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Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.