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Senior Scientist / Associate Principal Scientist – Peptide and Conjugation Chemistry

Location Gothenburg, Västra Götaland County, Sweden Job ID R-112637 Date posted 03/07/2022

AstraZeneca R&D, Gothenburg, Sweden seek to recruit a Senior Scientist or Associate Principal Scientist responsible for Peptide and Conjugation Chemistry within the Medicinal Chemistry department of the therapeutic area Respiratory and Immunology (R&I). 

AstraZeneca is one of the world’s most exciting biopharmaceutical companies. From scientists to sales, lab techs to legal, we’re on a mission to turn science into life-changing medicines that improve patients’ lives and benefit society. AstraZeneca is committed to the development of the next generation innovative medicines. 

The Department of Medicinal Chemistry in the therapeutic area of Respiratory & Immunology is focused on the delivery of Small Molecule (SM) and New Modalities (NM) clinical candidates. In this context, we are focused on increasing our capabilities around novel peptide and oligonucleotide-based molecules / conjugates for the treatment of respiratory and immunological diseases.

What you'll do
You will be part of a team of scientists dedicated to discovering drugs based on peptide and oligonucleotide chemistry. For this permanent position, you should have a strong background in the design, synthesis, bioconjugation, purification and characterization of novel peptide-based molecules. Your level of professional experience will be relevant for your initial career level (Senior Scientist/Associate Principal Scientist).

Major Duties and Responsibilities:

  • Peptide design, synthesis and optimization

  • Design and execution of various (bio)conjugation techniques to prepare novel peptide-oligonucleotide conjugates

  • Contribution to identify novel delivery technology applicable to peptide and/or oligonucleotide therapeutics

  • Effective collaboration with project team members and colleagues in other departments

  • Driving internal / external scientific visibility through publications and scientific presentations 

Essential for the role

  • PhD in Bio-/Organic Chemistry 

  • Expertise in peptide and/or conjugation chemistry 

  • Knowledge of recent developments in peptide and (bio-)conjugation chemistry

  • Strong scientific curiosity in novel technology and methods

  • Excellent communication and collaboration skills

Desirable for the role

  • Knowledge of tissue specific delivery of peptides and/or oligonucleotides is a bonus

  • Experience in pharmaceutical drug discovery of peptide drug candidates is a plus

Why AstraZeneca?
Our Gothenburg site is one of AstraZeneca's three strategic R&D centers. Here, you'll feel a global atmosphere in a multinational environment. Collaboration comes in all forms - across teams, functions, countries and even companies.
With more than 2,400 employees from over than 50 countries, our vibrant Gothenburg site is a truly inspiring place to work. Here, the history and future of scientific breakthrough come together. We believe that the diversity of our people is crucial to bringing new discoveries to life.

What's next!
If you are ready to make a difference - apply today, and we'll make it happen together! For more information about the position please contact Wu Su, Team Leader, New Modalities Medicinal Chemistry, by email: or via LinkedIn. We welcome your application until August 14, 2022.
NOTE - Due to our summer vacation period in Sweden during July-August, the screening process may take a bit longer than usual. Thanks for your understanding and we will get back to you as soon as possible when we are back at work.

Where can I find out more?
Our Gothenburg site:
Life in Gothenburg:
Culture and atmosphere of the Gothenburg site:

Relocate to Gothenburg:

50056715 E SCCY R&D BioPharmaceuticals

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