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Senior Scientist

Location Gaithersburg, Maryland, United States Job ID R-157522 Date posted 23/01/2023

Do you have expertise in the analysis and interpretation of multi-omic data from complex immunopathologies? Would you like to apply your expertise to the development of new immuno-oncology therapies in a company that follows the science and turns ideas into life-changing medicines? Be a part of our Early Data Science team where you can develop and apply cutting edge computational tools to our early oncology portfolio and publish in high impact journals. 

AstraZeneca is a global, science-driven biopharmaceutical company. We are dedicated to discovering, developing, and delivering innovative, meaningful medicines and healthcare solutions that enrich the lives of patients. The vision of AstraZeneca Oncology is to redefine cancer, redefine our solutions to cancer, and restore patients' lives.  

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world.  This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you’ll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams. 

The Early Data Science team works with our oncology drug project teams throughout the research and early development pipeline, from new target discovery to translational medicine and clinical trials. Our global group aligns its activities to AstraZeneca’s primary areas of focus in Oncology: immuno-oncology, DNA damage response, tumor drivers & resistance, epigenetics, cell therapies and antibody-drug conjugates.

Excitingly the team is growing to meet the data science challenges of new cancer therapies such as cell therapy. There exists an opportunity for a dedicated and motivated bioinformatician with strong expertise in immune system and/or cancer omics to join the group as a senior scientist. The role will work with our Immuno-Oncology, Circuits-Engagers, Cell Therapy (ICC) drug project teams to deliver useful insights from clinical and pre-clinical data and to develop bioinformatic capabilities that power our ability to do this.

Main Duties and Responsibilities:

  • Work as part of drug project and clinical teams to understand their scientific and technical challenges and proactively impact these using bioinformatics. 

  • Apply data and knowledge analytics to deliver actionable insight driving discovery and development of the next generation of immuno-oncology medicines.

  • Discover, design and code innovative ways to identify and visualise meaningful patterns in complex data to facilitate biological interpretation.

  • Work with our labscientists to influence experiment design and generation of data assets for hypothesis testing and validation.

  • Share code and train peers and bench scientists in the tools critical to understanding complex data.

  • Collaborate with industry and academic partners.

  • Publish your work in high impact journals.

Minimum Qualifications:

  • 2 years of industry experience

  • Relevant PhD (or equivalent graduate degree plus proven applied experience), combining: 

    • Technical expertise in applied bioinformatics, computational biology, data science or biostatistics. 

    • A deep understanding of the molecular mechanisms driving cancer or immunological disorders. 

  • Reproducible R programming and visualisation expertise in Unix environments.  

  • Skilled in effective communication of complex data to a non-expert. 

  • Expertise in the organisation, analysis and interpretation of multi-omic data to reveal drug action and resistance mechanisms, tumor microenvironment subtypes, clinically relevant biomarkers and pan-cancer stratifications.  

  • Capability of successfully managing multiple simultaneous projects. 

  • Working effectively within cross-disciplinary science teams, including with functional leaders. 

  • Experience of contributing to the research community through conferences, peer-reviewed publications and source code. 

Why AstraZeneca

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients, ­and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth, and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next?

Are you already envisioning yourself joining our team? Good, because we can’t wait to hear from you!

Competitive salary and benefits package on offer

Competitive salary and benefits package on offer. The successful candidate will have access to pension contributions, A performance recognition scheme and a competitive, generous remuneration package.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

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