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Senior Scientist - Protein/Vector Engineering for Cell Therapy

Location Gaithersburg, Maryland, United States Job ID R-148653 Date posted 21/09/2022

Senior Scientist - Protein/Vector Engineering for Cell Therapy

Location: Gaithersburg, MD

Why AstraZeneca

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

Do you have expertise in, and passion for, protein and cell engineering? Would you like to apply your expertise to shape the next generation of cell therapies in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

This Opportunity

The focus of the Oncology Cell Therapy team within the Biologics Engineering department is to bring expert capabilities in protein and vector engineering to bear in the development of cell therapeutics. As part of the exciting Oncology Cell Therapy Unit at AstraZeneca, we work closely and collaboratively with colleagues who specialize in tumor immunology, T cell biology and cell product manufacturing to engineer life changing cellular medicines for patients. Our culture is highly collaborative, fast-paced and innovative.

In this role, you will be focused on protein and vector engineering aspects of cell therapy. This includes the design and optimization of synthetic receptors such as CARs, TCRs or other proteins to control cell biology as well as the viral and non-viral vectors used to deliver these engineered proteins into therapeutic cells. You will work closely with a diverse set of colleagues in the exciting new Oncology Cell Therapy Unit at AstraZeneca to deliver cutting-edge oncology cell therapies.

Educational Requirements:

  • Ph.D. in biochemistry, molecular biology, cell biology, immunology or other relevant discipline.

Required Skills:

  • Experience with protein engineering for the purpose of controlling cell biology
  • Strong molecular biology skills
  • Experience with viral and non-viral gene delivery systems and their optimization
  • Consistent record of conceiving research projects and carrying out their execution

Desirable Skills

  • Broader immunology knowledge
  • Familiarity with design and optimization of CAR-T therapies
  • Computational protein design/modeling

About Our Gaithersburg Oncology Hub

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you’ll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.

So, what’s next?

Are you already envisioning yourself joining our team? Good! We can’t wait to hear from you!

If you’re curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.

Closing Date: October 21, 2022

Competitive remuneration and benefits apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

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Glassdoor logo Rated four stars on Glassdoor

Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.