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Senior GMAL/Global Medical Affairs Leader - Immuno-Oncology

Location Gaithersburg, Maryland, United States Cambridge, England, United Kingdom Job ID R-108259 Date posted 14/05/2021

Do you have expertise in, and passion for Medical Affairs in Oncology? Would you like to apply your expertise to impact the Sr GMAL/Global Medical Affairs Leader - IO role in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

AstraZeneca’s vision in Oncology is to help patients by redefining the cancer-treatment paradigm, with the aim of bringing six new cancer medicines to patients between 2013 and 2020. A broad pipeline of next-generation medicines is focused principally on four disease areas - breast, ovarian, lung and hematological cancers. As well as other tumor types, these are being targeted through five key platforms - immunotherapy, the genetic drivers of cancer and resistance, DNA damage repair, HER2 and antibody drug conjugates, underpinned by personalized healthcare and biomarker technologies.

As a Sr. GMAL/Global Medical Affairs Lead (GMAL) in Oncology, you will play a pivotal role in channelling our scientific capabilities to make a positive impact on changing practice and patients’ lives.

The GMAL will provide medical leaderhip for the GMT (Global Medical Team), lead the medical strategy and execution of key deliverables to support launch and lifecycle management globally. This GMAL role will report to the Head of IO multi-indication team.

Core accountabilities of this role are:

  • Provide a leadership and coordinated approach to building AstraZeneca’s medical leadership and deliver medical insight into the development and execution of a medical affairs strategy.
  • Oversee and support the development and execution of an integrated medical plans (evidence generation and scientific communications), interactions with global external experts, scientific exchange, medical education, diagnostics and patient centric initiatives. 
  • Lead development and execution of global External Sponsored Research (ESR) and Early Access Program (EAP) strategies and align with AstraZeneca Global Medical Affairs and Marketing Countries on local implementation.
  • Partner closely with cross-functional colleagues, including marketing companies, development, early research, regulatory, commercial, access, health outcomes and other key functions to help build alignment on key initiatives including optimal approach to data generation, scientific communication and supporting access.
  • Interface with internal and external stakeholders to enhance the scientific and clinical understanding of the brand with other members of the Medical Affairs teams


  • Advanced scientific degree (MD, PhD, PharmD)
  • Medical Affairs experience or relevant medical/clinical experience minimum.
  • Understanding of drug development and commercialization processes including understanding of outcomes research /payer access issues
  • Oncology experience
  • Proven ability to generate, analyze and interpret clinical trial and published data
  • The candidate is expected to have strong leadership skills, strategic thinking and ability to work effectively with cross-functional teams including development, marketing, and access
  • Track record of successfully developing and executing Medical Plans both in terms of evidence generation, scientific communications and external expert engagements
  • Ability to manage multiple projects and products simultaneously to ensure timely, on-target and within budget accomplishment of tasks
  • Good communication and presentation skills in English

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

50201108 G MABM Oncology

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Glassdoor logo Rated four stars on Glassdoor

Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.