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Postdoctoral Fellow: Machine Learning to Predict Cardiovascular & Renal Outcomes

Location Gaithersburg, Maryland, United States Waltham, Massachusetts, United States Job ID R-099638 Date posted 05/11/2021

Postdoctoral Fellow: Machine Learning to Predict Cardiovascular & Renal Outcomes

Gaithersburg (MD) or Boston (MA), US

Competitive Salary, Bonus & Benefits

About AstraZeneca:

AstraZeneca is a global, science-led, patient-centered biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious disease. But we’re more than a global leading pharmaceutical company. At AstraZeneca, we‘re dedicated to being a Great Place to Work where you are empowered to push the boundaries of science and fuel your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society.

About the Postdoc Program:

Bring your expertise, apply your knowledge, follow the science and make a difference.

AstraZeneca’s Postdoc Program is for self-motivated individuals looking to tackle exciting, high impact projects in a collaborative, engaging and innovative environment. You'll work with peers and professionals from a diverse group of backgrounds, and a world class academic mentor specifically aligned to your project. We'll help you develop valuable networks which support your research and future career development!

AstraZeneca Postdocs are respected as specialists and encouraged to speak up. They lead ground-breaking drug discovery and development research projects. Our vibrant, multi-disciplinary scientific teams empower and support our Postdocs, and we encourage them to share their research at conferences, publish papers, achieve their goals and make a difference to our patients.

You'll learn from industry leaders working on innovative research across our organization. Our Postdoc Training Program will support you to develop transferrable skills from influencing others to shape the agenda, to data analysis.

Are you ready to explore this exciting next step in your research career? Apply today!

About the Opportunity:

In this role you will join a team of quantitative clinical pharmacologists and pharmacometricians who work collaboratively with experts across AstraZeneca to push the boundaries of science to deliver life-changing medicines to patients. Together, you’ll advance our research into the use of machine learning, artificial intelligence tools and computational modelling to predict individual long-term risk of major cardiovascular events (MACE) and renal disease.

You’ll analyse AstraZeneca’s data from approximately 180,000 patients in cardiovascular clinical trials. By exploring patient characteristics and short-term biomarker changes you will aim to generate insights and recommend actions that improve treatment selection for patients with diabetes and cardiovascular disease. This is a unique opportunity to make an impact by improving predictions of therapeutic response to different drug classes and characterizing disease progression over time. This research has the potential to help shape AstraZeneca’s cardiovascular and renal disease clinical trials strategy.

Qualification, Skills & Experience


  • A PhD (or equivalent) in a quantitative discipline (engineering, pharmacometrics, pharmacology, biostatistics, applied math, computational math, or related)

  • Proficient in data analysis, machine learning, and/or computational modelling in R, python or similar software

  • Interest in applying quantitative tools to solve clinically-meaningful problems

  • Strong communications skills, including manuscript writing, oral presentations and the ability to communicate technical material to a broad audience

  • Ability to see opportunities, learn, and apply that learning to solve problems and drive innovation

  • Collaborative, with an inclusive approach to teamworking


  • Working knowledge of pharmacology and physiology

  • Prior experience of working with clinical data

Ready for an exciting, rewarding challenge? Apply today!

Advert Opens: 5th November, 2021

Advert Closes: 12th December, 2021

This is a 2-year program, with a merit-based potential 3rd year.

AstraZeneca has taken critical steps to protecting colleagues, loved ones, and patients from COVID-19 and its variants.  COVID-19 vaccination is required for all US employees, and weekly PCR COVID-19 testing is required for those who are unvaccinated or have an approved accommodation.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

50056739 C SCGE R&D BioPharmaceuticals

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Glassdoor logo Rated four stars on Glassdoor

Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.