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GI Medical Head, US Medical Affairs

Location Gaithersburg, Maryland, United States Job ID R-123690 Date posted 12/12/2021

Do you have expertise in, and passion for Medical Affairs in Oncology? Would you like to apply your expertise to impact the GI Medical Head, US Medical Affairs role in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

AstraZeneca’s vision in Oncology is to help patients by redefining the cancer-treatment paradigm, with the aim of bringing six new cancer medicines to patients between 2013 and 2020. A broad pipeline of next-generation medicines is focused principally on four disease areas - breast, ovarian, lung and hematological cancers. As well as other tumor types, these are being targeted through five key platforms - immunotherapy, the genetic drivers of cancer and resistance, DNA damage repair, HER2 and antibody drug conjugates, underpinned by personalized healthcare and biomarker technologies.

Mission & Objective Description:

The GI Medical Head in US is responsible for the development and implementation of GI medical strategy in the US. In this leadership role, the GI medical head leads a team of Medical Leads and Medical Directors to prepare for multiples launches across multiples assets across multiple tumor types in GI cancers (ADC, IO, DDR, etc)

  • Drive scientific leadership in the delivery of robust and actionable KOLs insights and patient perspectives in the drug development and commercialization of innovative medicines across GI cancers.
  • Lead the development and delivery of the US GI medical affairs strategy that encompasses multiple assets in multiple GI cancers with budget and staff accountability, supporting lifecycle management.
  • Provide expertise, to ensure greater effectiveness, integration and appropriate adoption of our innovative medicines.


  • Accountable to deliver an integrated and timely medical evidence plan to address the need of patients, HCPs and patients. (Interventional, observational, ESRs, HEOR)
  • Accountable for leading and managing the immuno-oncology medical team, creating a great place to work that fosters innovation and high performance.
  • Medical Affairs direct reports: medical affairs directors and Leads who are developing the Medical Strategies and delivering US Medical Plans for each indications/brand, as well as partnering with the cross-functional team in the development of the Brand Strategic Plan and Launch Readiness Plans
  • Lead the GI strategy  (across GI tumors and assets) for US medical and develop and deliver on the GI strategy plan.
  • Motivate, inspire and lead the team by creating an environment of shared goals, clear responsibilities, talent development/retention, and continuous improvement.
  • Effectively develop, communicate, and drive a long-term vision and plan for medical affairs program, anticipating and addressing potential issues.
  • Responsible for identifying best practices and capturing innovative ideas in Medical Affairs (both internally and externally) and sharing with the enterprise and helping foster an accountable, entrepreneurial team. Accountable for Medical insight generation to input to TA, Product and Brand teams.
  • Responsible for over-sight of opinion leader engagement to discuss therapy area and product strategy medical topics and generate insights to address unmet patient needs across the patient pathway.
  • Strategic thinking and engagement in the future of medicine
  • Engage actively with the cross functional and Global teams
  • Efficiently manage budgets and resources, including budget planning for future activities within assigned disease area.

Requirements and preferred experience

  • MD Strongly Preferred (specialty training) 5+ years of relevant clinical experience in the TA; PhD possible; ideally Academic experience in the relevant TA.
  • Pharmaceutical experience of 5+ years
  • Experience and proven ability to lead cross functional teams and build strong external and internal relationships with diverse stakeholders
  • Build and lead high performing cross-functional teams collaboratively.
  • KOLs engagement experience, ideally in the field of GI cancers.
  • Have technical expertise in clinical trial design and all stages of clinical trial conduct (Trial design, Start-up, Execution, Analysis, Reporting), including phase 3b/4, RWE as well as ESRs management
  • Knowledge of current clinical practice in Oncology, with ideally strong expertise in GI cancers
  • Translational medicine, population-based real-world research
  • Bridging with integrated care management & Quality improvement pathways
  • Understanding of Health Outcomes Research including Patient-reported outcomes

About Gaithersburg
Our Gaithersburg, Maryland facility crafts life-changing medicines for people around the world. This campus employs more than 3,500 specialists in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most ground breaking technology and lab spaces, all designed to encourage collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to fostering a culture of inclusion and collaboration.

The Gaithersburg site offers various amenities to help boost efficiency and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you’ll find newly-designed, activity-based work spaces to suit a variety of working styles while strengthening collaboration between teams.

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn

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AstraZeneca has taken critical steps to protecting colleagues, loved ones, and patients from COVID-19 and its variants.  COVID-19 vaccination is required for all US employees, and weekly PCR COVID-19 testing is required for those who are unvaccinated or have an approved accommodation.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

50201108 G MABM Oncology

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Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.