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Bioinformatics Scientist I - Microbial Sciences

Location Gaithersburg, Maryland, United States Job ID R-054717 Date posted 07/01/2019

At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We’re focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we think we can really change the course of medicine and bring big new ideas to life. Asa Bioinformatics ScientistinGaithersburg, MD,you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives. You will be a part of the Microbial Sciences group, where you will study the microbiome in drug development utilizing various molecular tools. The position offers a unique opportunity for a talented individual to work in a dynamic and innovative environment. S/he will not only interact with highly accomplished scientists in the Microbial Sciences group but will also be collaborating with translational and clinical scientists in other therapeutic areas to develop his/her career at the interface of basic research and drug discovery.

Major Duties and Responsibilities:

The Scientist will use next generation sequencing or deep sequencing technologies to examine mucosal microbiota in animal and human samples to understand microbiome changes during disease progression and from drug treatment intervention. The candidate is expected to have a strong analytical ability and may conduct experiments in the wet lab.


Education: PhD degree (0-3 years of academic/industrial experience after post doc) with strong background in bioinformatics, statistics or related discipline.


  • Extensive experience analyzing microbiome-based sequencing data from preclinical and clinical samples.
  • Experience conducting statistical analyses to interpret experimental results and design appropriately powered preclinical studies a plus.
  • Demonstrated ability to initiate and conduct high-level novel research projects with a strong track record of developing creative solutions to complex problems.
  • Must be motivated and capable of working independently as well as collaboratively with experience leading one or more scientists.
  • The applicant must have strong written and verbal communication skills with a strong publication record.
  • Multi-omic analysis and pipeline development experience is a plus.

Special Skills/Abilities:

Skilled at developing bioinformatics pipelines to analyze 16s rRNA, ITS, metagenomic whole genome and virome sequence data from microbiome samples.

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. 

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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