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Production Technician I-Day Shift

Posted date 03/17/2023
Contract type Full_time
Job ID R-161823
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What you'll do

As a member of our Operations team, you’ll be on the front line, directly impacting patients by making sure we manufacture our products effectively, quickly and collaboratively. Every day, you’ll experience fresh challenges as you navigate the ever-changing landscape of Operations – which means you’ll have plenty of opportunities for personal and professional development. Backed by a supportive team, be part of accelerating our operational excellence with innovations in cutting-edge science, Lean ways of working and fast changing digital technologies.

In our fast-paced, growing environment, embrace an exciting opportunity to build a long-term, varied career. Experience leading edge digital innovations such as artificial intelligence and augmented reality that drives efficiencies and keeps a balanced workload. Enjoy varying shifts in a regulated but stimulating atmosphere. And gain invaluable experience and exposure in a team that wants to see you succeed.

Why Global Operations at AstraZeneca?

From molecule to medicine, our pipeline to deliver to patients is ever-growing and increasingly complex. Our Operations Team brings the Research & Development pipeline to life, from development and manufacturing, through to testing and delivery. We have the ambition to make our processes quicker, more affordable and more sustainable, leading to better outcomes.

It makes us proud to know we’re working with medicines that address unmet needs. With every decision we make, we are conscious of our very clear responsibility to deliver. So, we create a culture of continuous improvement – driven by our people.

With teams across 25 locations and a reach into global communities, your ideas can become a reality at scale, with the potential to genuinely improve the lives of patients and their families. Join the team where everyone feels a personal connection to the people that we impact.

Success Profile

Our success profile gives you a better idea of whether the job is right for you. These are the behaviours you’ll need in order to thrive.

Problem solver

Disciplined thinkers and doers, we thrive in our often intense and varied environment, seeking out new challenges and working towards new solutions. As an avid problem solver, you’ll do well here.

Eager to learn

If you’re proactive with a thirst for knowledge, we’ll provide you with every resource to grow. We’ll give you what you need to achieve autonomy, advance your career and work with advanced technologies.

Open to change

In a global biopharmaceutical, things change quickly – and it’s up to us in Operations to make sure that change goes smoothly. The ability to be adaptable plays a huge role in whether our continuous improvement succeeds.

Patient-first mindset

The medicines you manufacture, package and deliver in Operations help people. If you have the passion and the drive to make people’s lives better – then this is the place for you.


Job ID R-161823 Date posted 03/17/2023

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.

Our Frederick Manufacturing Center (FMC) is one of 30 production facilities in 18 countries that creates life-changing medicines for people around the world. This biologics manufacturing facility makes a direct contribution to treating people with cancer, respiratory and autoimmune conditions across the globe. It’s challenging but highly rewarding work, involves more than 675 talented people throughout the manufacturing lifecycle and supporting office functions. We work hard to deliver life-changing medicines to patients, and we take time to have fun and celebrate our accomplishments. From catered site festivities to competitive events, community outreach activities, environmental and wellness showcases and team-building events, we take time to recognize our achievements. The FMC site is also an award-winning employer and has been recognized as a ‘Top 50’ Business in Frederick and awarded Frederick County’s ‘Best Place to Work’ distinction in 2015 and 2019. Come join our award-wining team and support the manufacture of life-changing medicines for patients across the world.

Why Join Operations?

Here we turn molecules to medicines, bringing our Research & Development pipeline to life through a rigorous process of development, manufacturing, testing and delivery. In our fast-paced, growing environment, embrace an exciting opportunity to build a long-term, varied career. With a huge variety of global opportunities and learning from other teams this is the place to embrace lifelong learning and build capabilities, setting your own direction and pace.

If you have the passion and the drive to accelerate growth and make people’s lives better – then this is the place for you.

Shift Schedule: This is a 12 hour shift,  2,2,3 schedule (2 days on, 2 days off, 3 days on, etc.), from 6 am - 6:30 pm.

What you’ll do:

As a Production Technician I-Day Shift in the Manufacturing group at Frederick, MD, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.

You will be responsible for the Production Technician duties, which will include:

  • Operation of upstream / downstream / central services processing equipment according to established SOPs. This equipment includes but is not limited to bioreactors, TFF skids, biological safety cabinets, incubators, chromatography skids, UFDF skids, autoclaves, washers, and product hold tanks.

  • Upstream / downstream / central services processing according to established manufacturing production records (MPRs & SPRs) in accordance with cGMPs.

  • Provide training on these activities and able to operate process equipment.

  • Revise cGMP documentation.

  • Basic equipment knowledge to perform first line trouble shooting and root cause analysis.

  • Ability to deal with problems involving a few concrete variables in standardized situations.

Minimum Qualifications:

  • BS/BA degree preferred. Associates degree and/or High School Diploma acceptable with experience

  • 0-1 yrs. experience with Bachelors

  • 1-2 yrs. experience with Associates

  • 3-5 yrs. experience with High School Diploma

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be an excellent fit, please share this posting with them.

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About Operations

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

Reasons to Join



We offer training as soon as you join. This will leave you feeling confident about the job ahead and excited to get started. From there, you have the opportunity to complete qualifications, develop into a leader within your area of expertise and inspire others to reach their potential.

Future-focused technology

With automation and machine learning changing the Operations environment, we are investing in cutting-edge technologies that improve flow whilst making you more effective in your work. And our Lean ways of working will help you innovate with a digital-first mindset.

Work/life balance

Whether you’re working around studies, parenthood or caring for loved ones, our shift patterns help make work manageable and life a lot easier. It’s all part of our commitment to making Operations the place for agile and committed innovators.


In Operations, you can move both upwards and sideways. Whether you want to aim for management, use your skills in a different department or even help other sites achieve consistency, we want our people to grow in the direction that is right for them.

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Glassdoor logo Rated four stars on Glassdoor

Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.