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Simulation & Analytics Lead – Health Technology Assessment

Location Cambridge, England, United Kingdom Gaithersburg, Maryland, United States Job ID R-151647 Date posted 23/11/2022

Simulation & Analytics Lead – Health Technology Assessment

Cambridge, UK or Gaithersburg, US

Here you’ll have the opportunity to make a meaningful difference to patients’ lives.

With science at its heart, this is the place where breakthroughs born in the lab become transformative medicines – for the world’s most complex diseases.

Answer unmet medical needs by pioneering the next wave of science, focusing on outcomes and shaping the patient ecosystem.

With our ground-breaking pipeline, the outlook is bright. Be proud to be part of a place that has achieved so much, yet is still moving forward.

There’s no better time to join our global, growing enterprise as we lead the way for healthcare and society.

What you’ll do:

Main Accountabilities:

  • Develops strategic approach and technical delivery of HTA statistical analyses for assigned medicine, and across franchises. This will include network meta analyses (NMA), population-adjusted and standard indirect treatment comparisons (ITC), utility analyses, survival analysis, and other advanced analytics used for HTA and wider market access

  • High level of interactive communication and influencing cross-functional partners and external stakeholders, understanding the payer and industry perspective to developing and implementing innovative HTA methods and solutions to complex problems.

  • Recognises and applies the value of HTA techniques to inform market access and wider cross functional decision-making

  • Co-develops the HTA simulation publication strategy for specific tumours, working with Health Economic and Payer Evidence (HEPE) and other cross functional partners, along with authoring innovative publications

  • Provides leadership and input to internal HTA simulation and analytics guidance documents

  • Develops the Payer Analysis Plan strategy and identifies analytical solutions to payer questions and challenges

  • Provides input to quality assurance of simulation and statistical analysis projects, contributing to global standards and ensuring best practice by keeping up to date with the relevant technical guidelines and recommendations.

Essential requirements:

  • Bachelors’ degree in mathematical sciences (e.g. mathematics, statistics, operations research, engineering) or quantitative social sciences (e.g. economics, health economics, health services research) or equivalent quantitative skill demonstration

  • Master’s degree in relevant field (as above) or substantial equivalent experience

  • Experience across multiple tumors and products as well as submission and defense in at least one HTA market

  • Experience in health economic modelling or similar relevant experience

  • Experience in oncology health economic modelling, survival analysis, utility analyses, and NMAs and Bayesian analyses.

  • Experienced in R/Winbugs/Stata/SAS and/or an advanced Excel user, including VBA

  • Technical knowledge of the changing HTA requirements globally and how to deliver against these

Desirable requirements:

  • PhD in a relevant quantitative discipline

  • Previously worked in Pharma (at a local or global level) with launch experience

  • Experience across multiple HTA systems

  • Skills and Capabilities:

    • Statistical software / programming coding

    • Population adjusted indirect comparisons

    • Treatment switching analysis

    • Can represent the Company externally

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

50056657 F CDHE

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Glassdoor logo Rated four stars on Glassdoor

Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.