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Clinical Information Science - Principal

Location Cambridge, England, United Kingdom Job ID R-082990 Date posted 05/28/2020
Clinical Information Science - Principal

Location – Cambridge (UK)

At AstraZeneca our Oncology Biometrics department is an integral part of the Oncology R&D organisation. We drive excellent design in order to generate the appropriate data needed for quality decision making.  The goal of Oncology Biometrics is to deliver value to the pipeline by excellence in delivery, improved decision making and engaging and shaping the external environment whilst accessing and implementing innovative solutions. Would you like to be a part of helping us achieve this ambition? Explore the possibility of joining us as a Clinical Information Science, Principal within Oncology.

Would you like to be a part of helping us achieve this ambition? Explore the possibility of joining us as a Clinical Information Science Principal (CISP) within Oncology & Immuno-Oncology.

Even as research and development continues to break boundaries in how we understand and fight cancer, there are still more than eight million lives lost every year to the disease. This is why the optimal use of clinical information to shape our trials and subsequent portfolio of oncology products is crucial to us being able to deliver life-changing medicines to patients most in need. Would you be motivated to join us in our dedication to the cause of one-day helping to eliminate cancer as a cause of death?


In this role you will support global clinical directors and trial design teams in finding and structuring clinical information driving optimal designs for late stage oncology drug development. It sits within our Information Practice unit who enterprise reuse of clinical information and knowledge retention for better informed decision-making and clinical development.


Embedded within dynamic oncology drug project teams, you will ascertain and deliver the information clinical teams need to assist them in making decisions driving the drug development process. For example, using a variety of information sources such as ClinicalTrials.Gov, BioMed Tracker, and internal clinical databases.

You will also contribute to key drug meetings and committees by establishing the scope, goals and deliverables supporting business goals in collaboration with senior management and decision makers.

The significant areas for contribution are:

Clinical Design

  • Support decision-making in clinical design by identifying, extracting and presenting back meaningful facts and data via internal and external information sources
  • Building a repository of key data bringing together key historical decisions for wide team to use and refer to (build the memory of clinical trials ranging from Phase IIb thru registration and life cycle management)
  • Contribute to the design team by collaborating with project stakeholders to plan and schedule project timelines, while tracking project landmarks and preparing progress reports

Disseminate key clinical information

  • Using techniques such as: text mining, data visualisation, competitor intelligence, and bench-marking extract key relevant information proactively enabling clinical drug design decision makers to make timely and objective decisions
  • Facilitate access to complex information for the drug project and ensure access to and (re)use of clinical information, documents and data


To succeed in this opportunity, you will have a real passion for clinical data and information – in particular knowing what information you require, how to seek it out, and how to share it with the teams in an insightful way.

You’ll be excited by the prospect of being embedded within late stage oncology drug development projects. An excellent communicator with great listening skills, who can absorb information and respond in a concise manner.

In addition, you will also have:

  • Bachelors or advanced degree in a Life Science
  • Sound understanding of the pharmaceutical clinical drug development process (with a preference for late-stage drug development in oncology or immuno-oncology)
  • Good understanding of project management techniques and methods
  • Experience in clinical information or science information setting in the application of information and knowledge management (settings could include, but are not limited to clinical drug development, medical writing, medical affairs, clinical operations, competitor intelligence, regulatory intelligence)
  • Good organisational skills and the ability to multitask; can set priorities and follow a timeline
  • Great attention to detail

Salary - Competitive salary and company benefits apply

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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Glassdoor logo Rated four stars on Glassdoor

Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.