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Associate Principal Scientist Immuno-Oncology

Location Cambridge, England, United Kingdom Job ID R-067026 Date posted 11/29/2019

At AstraZeneca, we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We’re passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life.

AstraZeneca’s vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and to ultimately eliminate cancer as a cause of death. A broad pipeline of next-generation medicines is focused principally on four disease areas - breast, ovarian, lung and hematological cancers.

We are seeking a highly motivated Associate Principal Scientist Immuno-Oncology with deep scientific and technical expertise in tumor myeloid biology and a track record of successful leadership of cross-functional project teams to join our team in Cambridge, UK. As a Project Lead within the Immuno-oncology (IO) Bioscience team, you will play a pivotal role in identifying the next generation of innovative IO therapies, and in deepening our understanding of cancer immunology.

Main Duties and Responsibilities

Working in this scientific leadership role within the IO Bioscience team, you will apply your technical and scientific to discover innovative therapeutic approaches. As the bioscience lead on cross-functional project teams you will be responsible for developing and delivering pre-clinical pharmacology project strategy. You will matrix manage the project bioscience team, providing expert advice and mentorship, interpreting complex data and making high level recommendations. You will apply your influencing, coaching and mentoring skills to ensure effective cross-functional working within teams. You will stay up to date with the latest discoveries in tumor immunology, share your expertise both within and beyond the bioscience group, publish peer reviewed articles on your research and develop and lead external collaborations. You may also directly line manage bioscience team members, helping to set goals and objectives and coordinating their professional development.

Essential Requirements

  • PhD (or equivalent) in a biological science with at least several years of research experience post-PhD in academia or industry
  • Deep expertise in tumor myeloid biology, plus broad understanding and enthusiasm for tumor immunology and cancer therapies
  • General knowledge of biologics drug development

  • Track record of successful scientific leadership of cross-functional scientific project teams or an academic research group lead
  • Technical expertise in preclinical model systems that can be applied to cancer immunology research
  • Excellent scientific communication skills including both written reports (e.g. manuscripts) and oral presentations to broad and diverse audiences

Desirable Requirements

  • Experience working in the field of IO drug discovery
  • Authorship of patents, grants and/or publications in top-tier scientific journals
  • Line management experience

Next steps? Apply now!



AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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